NF1
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Official Full Name
neurofibromin 1 -
Synonyms
NF1;neurofibromin 1;neurofibromin;neurofibromatosis;von Recklinghausen disease;Watson disease;neurofibromatosis-related protein NF-1;WSS;NFNS;VRNF;FLJ21220;DKFZp686J1293
Recombinant Proteins
- Human
- Rat
- Chicken
- E.coli
- Baculovirus-Insect Cells
- Wheat Germ
- Mammalian Cell
- E. coli
- HEK293
- His
- His&Strep
- GST
- N-His&C-Myc
- His&Fc&Avi
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NF1-334H |
Recombinant Human NF1 Protein, His-tagged
|
E.coli | Human | His | ||
| NF1-01HFL | Recombinant Full Length Human NF1 Protein, His&Strep-tagged | Baculovirus-Insect Cells | Human | His&Strep | Full L. | |
| NF1-335H | Recombinant Human NF1, GST-tagged | Wheat Germ | Human | GST |
|
|
| NF1-3967R | Recombinant Rat NF1 Protein | Mammalian Cell | Rat | His |
|
|
| NF1-2983H | Recombinant Human NF1 protein(1566-1837aa), His&Myc-tagged | E. coli | Human | N-His&C-Myc | 1566-1837aa |
|
| NF1-32H | Active Recombinant Human NF1 Protein (1197-1528), N-His tagged | E.coli | Human | His | 1197-1528 |
|
| NF1-3625R | Recombinant Rat NF1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| NF1-3625R-B | Recombinant Rat NF1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
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| NF1-643C | Recombinant Chicken NF1 protein, His&Myc-tagged | E.coli | Chicken | His&Myc | 1-270a.a. |
|
Involved Pathway
NF1 involved in several pathways and played different roles in them. We selected most pathways NF1 participated on our site, such as MAPK signaling pathway,Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | ELK1,RAC3,TGFBR1A,PDGFAB,MAPK4,PPP5C,NLK2,NFKB1,FGF1,TNF |
| Ras signaling pathway | RASSF5,TBK1,RAP1B,GNG5,ANGPT2,PLCG1,FGF17,GNG11,FGF6,PDGFA |
Protein Function
NF1 has several biochemical functions, for example, GTPase activator activity,phosphatidylcholine binding,phosphatidylethanolamine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NF1 itself. We selected most functions NF1 had, and list some proteins which have the same functions with NF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylcholine binding | APOA4B.2,APOA2,APOA4A,APOA1A,VPS24,APOA1,CHMP2A,CHMP3,APOC1,GPR119 |
| GTPase activator activity | ARAP1,TBC1D19,AGFG1,RINL,ARHGAP36,PTPLAD1,SMAP1,RGS21,FAM13B1,ARHGAP29B |
| phosphatidylethanolamine binding | CD300A,MFGE8,PEBP1,ANXA11,ESYT2,LC3,PEMT |
| protein binding | SCARA3,MTAP,GRB10,CCDC25,APEH,RFC3,CXCL9,HSPB9,APOBEC3C,PDHB |
Interacting Protein
NF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NF1.
APP;PML;SUMO1;DYNC1H1;Sdc1;Sdc3;SDC2;Sdc2;Sdc4;pi3p
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References
- Reuss, DE; Habel, A; et al. Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms. ACTA NEUROPATHOLOGICA 127:565-572(2014).
- Ypsilantis, P; Lambropoulou, M; et al. A case of diffuse bilateral scrotal neurofibroma in a rabbit. JOURNAL OF SMALL ANIMAL PRACTICE 54:491-494(2013).
