NEK9

  • Official Full Name

    NIMA (never in mitosis gene a)- related kinase 9

  • Overview

    Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.

  • Synonyms

    NEK9;NIMA (never in mitosis gene a)- related kinase 9;serine/threonine-protein kinase Nek9;DKFZp434D0935;MGC16714;Nek8;NERCC;nercc1 kinase;nimA-related kinase 8;NIMA-related kinase Nek8;nimA-related protein kinase 9;never in mitosis A-related k

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Mouse
  • E.coli
  • Insect Cells
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • Flag
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
NEK9-1259H Recombinant Human NEK9, GST-tagged E.coli Human GST C-term-345aa
NEK9-1064 Active Recombinant Human NEK9 protein, GST-tagged Insect Cells Human GST 1-979; deleted fragment of 346-731
NEK9-1064H Active Recombinant Human NEK9, GST-tagged Sf9 Cells Human GST 1-979; deleted fragment of 346-731
NEK9-3000R Recombinant Rhesus monkey NEK9 Protein, His-tagged Mammalian Cells Rhesus macaque His
NEK9-66H Recombinant Human NEK9 protein, Flag-tagged, Biotinylated Insect Cells Human Flag 1-346;733-979 a.a.
NEK9-3876HCL Recombinant Human NEK9 293 Cell Lysate HEK293 Human Non
NEK9-0834H Recombinant Human NEK9 Protein (S2-L979), Tag Free Insect Cells Human Non S2-L979
NEK9-0835H Recombinant Human NEK9 Protein (S2-L979), GST tagged Insect Cells Human GST S2-L979
NEK9-2819R Recombinant Rhesus Macaque NEK9 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
NEK9-2819R-B Recombinant Rhesus Macaque NEK9 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NEK9-2902H Recombinant Human NEK9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
Nek9-4370M Recombinant Mouse Nek9 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    NEK9 involved in several pathways and played different roles in them. We selected most pathways NEK9 participated on our site, such as Activation of NIMA Kinases NEK9, NEK6, NEK7,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitotic Prophase TMEM188,MCPH1,CTDNEP1A,GORASP2,CTDNEP1,BLZF1,DULLARD,ENSAB,VRK2,SETA
    M Phase ANKLE2,USO1,KIF2A,SGOL2,CDCA8,SETB,CENPP,NIPBL,CCDC99,ZWILCH
    Activation of NIMA Kinases NEK9, NEK6, NEK7 NEK6,NEK7
    Nuclear Envelope Breakdown DULLARD,CTDNEP1A,CTDNEP1B,CTDNEP1,NEK7,TMEM188,CNEP1R1,NEK6
    Cell cycle SGOL2,CDK7,WEE1,DCTN2,PCM1,H3F3B.1,AKAP9,TMEM188,HDAC5,SET
    Nuclear Pore Complex (NPC) Disassembly NEK6,NEK7
    Cell Cycle, Mitotic LIN52,ESCO2,CTDNEP1B,DBF4,CDCA5,SGOL2,MYCA,KNTC1,CENPK,KIF2A

    Protein Function

    NEK9 has several biochemical functions, for example, ATP binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK9 itself. We selected most functions NEK9 had, and list some proteins which have the same functions with NEK9. You can find most of the proteins on our site.

    Function Related Protein
    protein binding WWC1,NAA50,FAM134B,STK39,PRKAA1,ECSIT,ABCG1,MYH10,ABLIM3,SLC1A1
    protein kinase binding ARHGEF7,ZBTB4,TRIM22,PARK2,CDH2,PIWIL1,FAM83D,SOCS1,DNM2,ZC3HC1
    metal ion binding ELMSAN1A,ZNF670,NR5A1A,NADK,NOB1,ELOF1,MUTYH,ADCY8,RXRBA,ZNF461
    protein serine/threonine kinase activity AKT3A,MAP3K8,MAPK8A,MAST2,PDPK1,RIPK1,LIMK2,BMPR1AA,PAK2,MAPK14A
    ATP binding PTK2AB,NLRP2,CHD8,HSPD1,BCKDK,MCCC2,MOV10B.2,ERCC6,ABL2,RARS2

    Interacting Protein

    NEK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK9.

    GABARAPL2;DYNLL1;PLK1;GABARAPL1

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All NEK9 Products

    Required fields are marked with *

    My Review for All NEK9 Products

    Required fields are marked with *