NEBL
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Official Full Name
nebulette -
Overview
This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. -
Synonyms
NEBL;nebulette;LIM-nebulette;actin-binding Z-disk protein;LASP2;LNEBL;FLJ53769;MGC119746;MGC119747
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- HEK293T
- HEK293
- GST
- His
- Myc&DDK
- His&GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NEBL-1246H | Recombinant Human NEBL, GST-tagged | E.coli | Human | GST | 201-550aa | |
| NEBL-10552M | Recombinant Mouse NEBL Protein | Mammalian Cell | Mouse | His |
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| NEBL-2224Z | Recombinant Zebrafish NEBL | Mammalian Cell | Zebrafish | His |
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| NEBL-6058C | Recombinant Chicken NEBL | Mammalian Cell | Chicken | His |
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| NEBL-1485H | Recombinant Human NEBL Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| NEBL-1820H | Recombinant Human NEBL Protein, His&GST-tagged | E.coli | Human | His&GST | Met1-Ala264 |
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| Nebl-4351M | Recombinant Mouse Nebl Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| NEBL-590H | Recombinant Human NEBL Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| NEBL-5997M | Recombinant Mouse NEBL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NEBL-5997M-B | Recombinant Mouse NEBL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NEBL involved in several pathways and played different roles in them. We selected most pathways NEBL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEBL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NEBL has several biochemical functions, for example, actin filament binding,cytoskeletal protein binding,filamin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEBL itself. We selected most functions NEBL had, and list some proteins which have the same functions with NEBL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tropomyosin binding | TNNT2A,TNNT3,LMOD2A,LMOD3,TMOD3,TMOD1,TMOD4,LMOD1,TMOD2,S100A6 |
| structural constituent of muscle | MYL6,MYBPC3,TTN,MYBPC1,MYL1,ASPH,MYH11,NEXN,PLEC,MYL6B |
| actin filament binding | VCLA,MYH9,VPS16,ESPN,MYH11,FSCN2A,TMEM201,MYH9A,WIPF2B,ERMN |
| filamin binding | FBLIM1,ZNF664-FAM101A,HSPB7,FAM101A,FAM101B,TMEM67,PDLIM2,MICALL2 |
| cytoskeletal protein binding | CAPN1,PACSIN1A,FLNC,EZRA,LDB3,EPB41L5,FRMD5,RPH3AL,PACSIN3,PTPN4 |
| protein binding | SPHK1,SEPT5,HSPB9,SP3,EIF3J,ELK1,TNFRSF14,METTL13,CTDP1,ACTR8 |
Interacting Protein
NEBL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEBL here. Most of them are supplied by our site. Hope this information will be useful for your research of NEBL.
b2r8y4_human;HOMER3;TRIM27;GOLGA2;TRAF2;TRAF1;FLJ13057
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