NDUFA6
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -
Overview
NADH dehydrogenase1 alpha subcomplex subunit 6 is an enzyme that in humans is encoded by the NDUFA6 gene. -
Synonyms
NDUFA6;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (14kD, B14);NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6;B14;CI B14;complex I B14 subunit;LYRM6;NADHB14;CI-B14;Complex I-B14;LYR motif-containing protein 6;NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 6;NADH-ubiquinone oxidoreductase B14 subunit;NDUA6_HUMAN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NDUFA6-10520M | Recombinant Mouse NDUFA6 Protein | Mammalian Cells | Mouse | His |
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| NDUFA6-11203Z | Recombinant Zebrafish NDUFA6 | Mammalian Cells | Zebrafish | His |
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| NDUFA6-5372C | Recombinant Chicken NDUFA6 | Mammalian Cells | Chicken | His |
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| NDUFA6-5971M | Recombinant Mouse NDUFA6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NDUFA6-5971M-B | Recombinant Mouse NDUFA6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| NDUFA6-679H | Recombinant Human NDUFA6 Protein (27-154 aa), GST-tagged | E.coli | Human | GST | 27-154 aa |
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Involved Pathway
NDUFA6 involved in several pathways and played different roles in them. We selected most pathways NDUFA6 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Parkinsons disease | ATP5A1,NDUFS3,NDUFV1,COX7A2,SNCAIP,SLC6A3,NDUFV3,UQCRC2,UBE1Y1,SLC25A4 |
| Oxidative phosphorylation | NDUFB8,NDUFB11,PPA2,COX7B2,ATP6V1B1,NDUFS4,ATP5I,PPA1A,ATP6V1E1B,ATP5J |
| Non-alcoholic fatty liver disease (NAFLD) | ADIPOR2,EIF2AK3,NDUFB2,LEP,PIK3CD,INS2,IL6R,MLXIPL,NDUFS1,MAPK9 |
| Metabolic pathways | ENO3,POLE4,DAO.2,AGL,PFKMB,PGM3,LDHBA,KCNG4,UGT2B7,EXT1A |
| Huntingtons disease | CASP9,NDUFA5,NDUFB5,DCTN1,EP300,TAF4B,COX5B,VDAC2,POLR2A,PLCB3 |
| Alzheimers disease | APH1B,NAE1,NDUFA7,NDUFS6,ATP5B,NDUFV2,APOE,ATP5E,PLCB2,UQCRC2 |
Protein Function
NDUFA6 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFA6 itself. We selected most functions NDUFA6 had, and list some proteins which have the same functions with NDUFA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | LRRN4,TMEFF2,OXR1A,TSX,CWC25,TMEM165,AIM1,GM2506,TARM1,GM4952 |
Interacting Protein
NDUFA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFA6.
SNCA;Ywhae;Hsd3b4
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References
- Aguiar, AS; Stragier, E; et al. EFFECTS OF EXERCISE ON MITOCHONDRIAL FUNCTION, NEUROPLASTICITY AND ANXIO-DEPRESSIVE BEHAVIOR OF MICE. NEUROSCIENCE 271:56-63(2014).
- Angerer, H; Radermacher, M; et al. The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:5207-5212(2014).
