NDUFA3
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -
Synonyms
NDUFA3;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 (9kD, B9);NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3;B9;complex I B9 subunit;CIB9;Complex IB9;NADH ubiquinone oxidoreductase B9 subunit;complex I-B9;NADH-ubiquinone oxidoreductase B9 subunit;CI-B9
Recombinant Proteins
- Human
- Mouse
- Mus musculus
- Pan troglodytes
- Pongo Abelii
- Gorilla gorilla gorilla (Western lowland gorilla)
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- GST
- His
- His&GST
- Non
- His&Fc&Avi
Involved Pathway
NDUFA3 involved in several pathways and played different roles in them. We selected most pathways NDUFA3 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | DNAI1,DCTN2,SIN3A,DNALI1,ITPR1,TGM2,NDUFB5,SLC25A5,SDHC,DCTN1 |
| Metabolic pathways | CBSA,POLR3GL,CYP2B19,ARG1,GULO,OCRL,DAO.3,GALNT14,QARS,NDUFB10 |
| Non-alcoholic fatty liver disease (NAFLD) | NDUFS8,NDUFC2-KCTD14,NDUFV1,PRKAG1,SDHC,NDUFB2,NDUFA5,ADIPOR1,ATF4,CDC42 |
| Oxidative phosphorylation | ATP6V0CA,UQCRC2,ATP6V1B2,ATP6V0D2,ATP5IB,ATP6V0E,NDUFV3,COX4I2,ATP5L,ATP6AP1 |
| Parkinsons disease | GNAL,UQCRC1,NDUFB2,PRKACA,SDHB,NDUFB7,UQCRQ,NDUFB6,GNAI2,PARK2 |
| Alzheimers disease | CASP7,GRIN1,NDUFS8,NDUFB2,ATP2A1,PLCB1,COX6C,CASP9,ATP5F1,SDHD |
Protein Function
NDUFA3 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFA3 itself. We selected most functions NDUFA3 had, and list some proteins which have the same functions with NDUFA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADH dehydrogenase (ubiquinone) activity | NDUFB4,NDUFAB1,NDUFB3,NDUFA5,NDUFA4,NDUFA2,NDUFA7,NDUFB9,NDUFA8,NDUFB5 |
Interacting Protein
NDUFA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFA3.
NDUFA6;Tgs1;TIMMDC1
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References
- Rose, AM; Mukhopadhyay, R; et al. A 112 kb Deletion in Chromosome 19q13.42 Leads to Retinitis Pigmentosa. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 52:6597-6603(2011).
- Rak, M; Rustin, P; et al. Supernumerary subunits NDUFA3, NDUFA5 and NDUFA12 are required for the formation of the extramembrane arm of human mitochondrial complex I. FEBS LETTERS 588:1832-1838(2014).
