NDRG4
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Official Full Name
NDRG family member 4 -
Overview
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms. -
Synonyms
NDRG4;NDRG family member 4;protein NDRG4;KIAA1180;SMAP 8;smooth muscle-associated protein 8;brain development-related molecule 1;vascular smooth muscle cell-associated protein 8;BDM1;SMAP8;SMAP-8;FLJ30586;FLJ42011;MGC19632;DKFZp686I1615
Recombinant Proteins
- Mouse
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- HEK293T
- E.coli
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NDRG4-10506M | Recombinant Mouse NDRG4 Protein | Mammalian Cell | Mouse | His |
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| NDRG4-4201Z | Recombinant Zebrafish NDRG4 | Mammalian Cell | Zebrafish | His |
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| NDRG4-3928HCL | Recombinant Human NDRG4 293 Cell Lysate | HEK293 | Human | Non |
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| NDRG4-1491H | Recombinant Human NDRG4 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| NDRG4-1491H-B | Recombinant Human NDRG4 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| NDRG4-2428H | Recombinant Human NDRG4 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Ndrg4-4326M | Recombinant Mouse Ndrg4 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| NDRG4-520H | Recombinant Human NDRG4 Protein, His-tagged | E.coli | Human | His |
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| NDRG4-5959M | Recombinant Mouse NDRG4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NDRG4-5959M-B | Recombinant Mouse NDRG4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| NDRG4-914HFL | Recombinant Full Length Human NDRG4 Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
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Involved Pathway
NDRG4 involved in several pathways and played different roles in them. We selected most pathways NDRG4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NDRG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NDRG4 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDRG4 itself. We selected most functions NDRG4 had, and list some proteins which have the same functions with NDRG4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | STX19,CCDC53,RAB22A,MAPK15,CHRNB2,TRAFD1,TTF2,RGS8,OLR1,SEPT11 |
| molecular_function | TMEM44,TTC21B,GM8677,CEP89,PDCD10B,M1AP,TUSC2B,RASSF7B,ZFP474,CTXN2 |
Interacting Protein
NDRG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDRG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDRG4.
ARL6IP1;AGTRAP;CMTM5;RABAC1
Resources
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References
- Liu, XP; Hu, XL; et al. Preparation and Application of Monoclonal Antibody Against hNDRG2. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 152:306-315(2009).
- Okuda, T; Kokame, K; et al. Differential expression patterns of NDRG family proteins in the central nervous system. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 56:175-182(2008).
- Nakada, N; Hongo, S; et al. Molecular characterization of NDRG4/Bdm1 protein isoforms that are differentially regulated during rat brain development. DEVELOPMENTAL BRAIN RESEARCH 135:45-53(2002).
