NDN
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Official Full Name
Ndn necdin -
Overview
This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed;exclusively from the paternal allele. Studies in mouse suggest that the protein encoded by this gene may suppress;growth in postmitotic neurons. -
Synonyms
NDN;necdin;Peg6;AI528698
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NDN involved in several pathways and played different roles in them. We selected most pathways NDN participated on our site, such as Adipogenesis,p75(NTR)-mediated signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adipogenesis | AHR,CTNNB1,E2F4,MEF2B,BMP1,FOXC2,KLF7,BMP3,RORAA,CISD1 |
| p75(NTR)-mediated signaling | MAGEH1,PRDM4,RTN4,RTN4R,OMG,BEX1,ZNF274 |
Protein Function
NDN has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,gamma-tubulin binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDN itself. We selected most functions NDN had, and list some proteins which have the same functions with NDN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | KCNA3,EBF3A,FOXC2,HOXA10,HMGA2,PITX1,EBF2,FOSL1,FIGLA,CREB3 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | ELF1,MEF2B,SMAD6,HOXA10,NKX6,BSX,FOXL2,RFX1,CTCFL,ARID3B |
| gamma-tubulin binding | CEP57,BLOC1S2,RAB11FIP5,SPATC1,LYN,NDRG1,MARK4,NME2,TUBGCP3,BLOC1S2A |
Interacting Protein
NDN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDN here. Most of them are supplied by our site. Hope this information will be useful for your research of NDN.
NCL;TMEM33;SEC61A1;RPS11;TRIM28;GOLGA4;EID3;EID2;EID2B;CERS2;NSMCE4A;MPP6;DHCR7;SRPRB;AUP1;EID1;EGFR;ARSE
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