MST1

  • Official Full Name

    macrophage stimulating 1 (hepatocyte growth factor-like)

  • Overview

    Mst kinases, members of the STE20 family of kinases, are upstream activators of MAPK pathways that regulate processes such as apoptosis, morphogenesis and cytoskeletal rearrangements. The amino-terminal kinase domain of Mst is considerably homologous to t

  • Synonyms

    MST1;macrophage stimulating 1 (hepatocyte growth factor-like);D3F15S2, DNF15S2, HGFL;hepatocyte growth factor-like protein;hepatocyte growth factor like protein homolog;MSP;NF15S2;macrophage-stimulating protein;hepatocyte growth factor-like protei

Recombinant Proteins

  • Human
  • Mouse
  • Rat
  • Chicken
  • Zebrafish
  • CHO
  • Mammalian Cells
  • E.coli
  • Insect Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • Non
  • His
  • His&T7
  • GST
  • DDK&Myc
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
MST1-186H Active Recombinant Human MST1 CHO Human Non 19-483;484-711 a.a.
MST1-188H Active Recombinant Human MST1 Mammalian Cells Human Non 484-711 a.a.
Mst1-599M Active Recombinant Mouse Mst1 CHO Mouse Non Met1-Glu716
MST1-10150M Recombinant Mouse MST1 Protein Mammalian Cells Mouse His
Mst1-1525M Recombinant Mouse Mst1 protein, His & T7-tagged E.coli Mouse His&T7 Pro469~Val704
Mst1-1526R Recombinant Rat Mst1 protein, His & T7-tagged E.coli Rat His&T7 Val489~Glu716
MST1-6766C Recombinant Chicken MST1 Mammalian Cells Chicken His
MST1-9446Z Recombinant Zebrafish MST1 Mammalian Cells Zebrafish His
MST1-1139HCL Recombinant Human MST1 cell lysate Human Non
MST1-0126H Recombinant Human MST1 Protein (G2-G711), Tag Free Insect Cells Human Non G2-G711
MST1-0127H Recombinant Human MST1 Protein (G2-G711), GST tagged Insect Cells Human GST G2-G711
Mst1-1122M Recombinant Mouse Mst1 Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc
MST1-2088H Recombinant Human MST1 Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
MST1-2704H Recombinant Human MST1 protein(371-470 aa), C-His-tagged E.coli Human His 371-470 aa
MST1-4457H Recombinant Human MST1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
MST1-4457H-B Recombinant Human MST1 Protein Pre-coupled Magnetic Beads HEK293 Human
MST1-5670H Recombinant Human MST1 Protein, GST-tagged Wheat Germ Human GST
MST1-5754M Recombinant Mouse MST1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MST1-5754M-B Recombinant Mouse MST1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MST1-6473HF Recombinant Full Length Human MST1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 711 amino acids

    Involved Pathway

    MST1 involved in several pathways and played different roles in them. We selected most pathways MST1 participated on our site, such as FoxO family signaling,Integrated Pancreatic Cancer Pathway,a6b1 and a6b4 Integrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with MST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    amb2 Integrin signaling HP,NIPAL1,ELANE,CYR61,MST1R,LPA
    FoxO family signaling ZFAND5,CSNK1G3,CSNK1G2,FBXO32,GADD45A
    a6b1 and a6b4 Integrin signaling MST1R,PMP22
    Integrated Pancreatic Cancer Pathway CASP12,BRF1,MYT1,NOXA1,TOP1,IL11,CD82,JUND,CST3,TOP2A

    Protein Function

    MST1 has several biochemical functions, for example, molecular_function,protein binding,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MST1 itself. We selected most functions MST1 had, and list some proteins which have the same functions with MST1. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function CCDC81,TRAM1L1,SOSTDC1A,MUP12,UBL3A,FAM69C,UBALD1B,PLEKHG3,UBXN7,TMEM198
    serine-type endopeptidase activity TMPRSS4B,KLK15,KLK1B4,Acr,EGFBP2,TMPRSS15,KLK1B9,CELA3A,PLG,PRSS28
    protein binding UBA52,RALY,CETN1,AJUBA,CCDC120,SOX5,FES,RAB9A,TDRKH,DMD

    Interacting Protein

    MST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MST1.

    MST1R;q99ib8-pro_0000045599;TMPRSS11D;ST14;MOB1B

    MST1 Related Signal Pathway

    Resources

    Gene Families

    Growth Factors

    Research Area

    Apoptosis Intracellular Kinases
    Histone Phosphorylation
    Inflammatory Mediators
    Intracellular Kinases in the Akt Pathway

    References

    • Xu, XL; Jaeger, ER; et al. Mst1 Directs Myosin IIa Partitioning of Low and Higher Affinity Integrins during T Cell Migration. PLOS ONE 9:-(2014).
    • Yao, HP; Zhou, YQ; et al. MSP-RON signalling in cancer: pathogenesis and therapeutic potential. NATURE REVIEWS CANCER 13:466-481(2013).

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