LYL1
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Official Full Name
lymphoblastomic leukemia 1 -
Overview
Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene. -
Synonyms
LYL1;lymphoblastomic leukemia 1;protein lyl-1;Lymphoblastic leukemia derived sequence 1;Protein lyl 1;lymphoblastic leukemia-derived sequence 1;Lyl-1;bHLHa18
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
LYL1 involved in several pathways and played different roles in them. We selected most pathways LYL1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with LYL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | BCL6,FLI1,Pdgfa&Pdgfb,RUNX1,PAX5,RELA,WHSC1,TFE3,HMGA2,ETV7 |
Protein Function
LYL1 has several biochemical functions, for example, DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LYL1 itself. We selected most functions LYL1 had, and list some proteins which have the same functions with LYL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | NFIXB,MITFB,ATF4B1,POU5F1,FOXI2,JUNBB,FOXD5,ELF2B,FOXA2,ZSCAN1 |
| RNA polymerase II regulatory region sequence-specific DNA binding | FOXF1,ZNF548,NFIL3,NME2,RARG,ZSCAN2,ATF5A,SUV39H1,GATA2B,ETV6 |
| protein dimerization activity | FBXW11B,MYCS,MSC,MYC,ARNTL1B,CLOCK,WWOX,PIP4K2AA,TWIST1B,HES6 |
| protein binding | MAP4K3,GFM2,MIS12,LGR4,TESK2,EVC2,LARP4B,KRTAP5-6,RUNX2,EPHB2 |
| DNA binding | WDHD1,NR2F1B,PPP1R8,MEIS2B,DNMT1,TAF1L,GLYR1,VDRA,EPAS1,PARP4 |
Interacting Protein
LYL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LYL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LYL1.
TRIM33
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References
- Goodings, C; Tripathi, R; et al. Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias. LEUKEMIA RESEARCH 39:100-109(2015).
- Gerby, B; Tremblay, CS; et al. SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells. PLOS GENETICS 10:-(2014).
