LTBP1
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Official Full Name
latent transforming growth factor beta binding protein 1 -
Overview
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] -
Synonyms
LTBP1;latent transforming growth factor beta binding protein 1;latent-transforming growth factor beta-binding protein 1;LTBP-1;TGF-beta1-BP-1;transforming growth factor beta-1-binding protein 1
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- E.coli
- Non
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LTBP1-29149TH | Recombinant Human LTBP1 | Wheat Germ | Human | Non | 98 amino acids |
|
| LTBP1-3500R | Recombinant Rat LTBP1 Protein | Mammalian Cell | Rat | His |
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| LTBP1-5465C | Recombinant Chicken LTBP1 | Mammalian Cell | Chicken | His |
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| LTBP1-9347M | Recombinant Mouse LTBP1 Protein | Mammalian Cell | Mouse | His |
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| LTBP1-3156R | Recombinant Rat LTBP1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
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| LTBP1-3156R-B | Recombinant Rat LTBP1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| LTBP1-317H | Recombinant Human LTBP1 Protein, His-tagged | E.coli | Human | His | Asp1424~Glu1721 |
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| Ltbp1-318M | Recombinant Mouse Ltbp1 Protein, His-tagged | E.coli | Mouse | His | Asp1415~Glu1712 |
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| LTBP1-319H | Recombinant Human LTBP1 Protein, His-tagged | E.coli | Human | His | 600-739 aa |
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| LTBP1-320H | Recombinant Human LTBP1 Protein, GST-tagged | E.coli | Human | GST | 455-804 aa |
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| LTBP1-4591H | Recombinant Human LTBP1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| LTBP1-5237M | Recombinant Mouse LTBP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LTBP1-5237M-B | Recombinant Mouse LTBP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
LTBP1 involved in several pathways and played different roles in them. We selected most pathways LTBP1 participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| TGF-beta signaling pathway | GDF6,CHD,BMP5,INHBB,LEFTY2,SMAD2,BMPR2A,SMAD6,RPS6KB1,RPS6KB2 |
Protein Function
LTBP1 has several biochemical functions, for example, calcium ion binding,microfibril binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LTBP1 itself. We selected most functions LTBP1 had, and list some proteins which have the same functions with LTBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transforming growth factor beta binding | HYAL2,TGFBR3,LTBP4,ENG,TGFBR1,ACVRL1,VASN,ACVR1,THBS1,TGFBR2 |
| calcium ion binding | EYS,ANXA13,MEX3B,PLCB4,DST,PTBP3,ANXA13L,NUCB2B,PCDH21,PVALB7 |
| protein binding | ANXA11,IMP3,NCOR2,C1QTNF8,FSTL1,CSNK2B,MAT2B,CIB2,DAPK2,SMUG1 |
| transforming growth factor beta-activated receptor activity | TGFBR1,BMPR2B,BMPR2A,TGFBR2,TGFBR3,ENG,ACVRL1 |
Interacting Protein
LTBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTBP1.
TGM2;PCOLCE;ATN1;TGFB1;FBN1
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