LRP12

  • Official Full Name

    low density lipoprotein receptor-related protein 12

  • Overview

    This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants.

  • Synonyms

    LRP12;low density lipoprotein receptor-related protein 12;low-density lipoprotein receptor-related protein 12;FLJ12929;ST7;suppressor of tumorigenicity 7 protein;DKFZp781F1053

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Zebrafish
  • Mouse
  • HEK293
  • Mammalian Cell
  • E.coli
  • Mammalian cells
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • His&GST
  • His&Fc&Avi
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
LRP12-196H Recombinant Human LRP12, His-tagged HEK293 Human His 33-492 a.a.
LRP12-2550R Recombinant Rhesus monkey LRP12 Protein, His-tagged Mammalian Cell Rhesus macaque His
LRP12-5374Z Recombinant Zebrafish LRP12 Mammalian Cell Zebrafish His
LRP12-9233M Recombinant Mouse LRP12 Protein Mammalian Cell Mouse His
LRP12-1749H Recombinant Human LRP12 Protein, His&GST-tagged E.coli Human His&GST Lys358-Cys514
LRP12-2370R Recombinant Rhesus Macaque LRP12 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
LRP12-2370R-B Recombinant Rhesus Macaque LRP12 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
LRP12-4230H Recombinant Human LRP12 Protein (Asn28-Ile488), C-His tagged Mammalian cells Human His Asn28-Ile488
LRP12-4694H Recombinant Human LRP12 Protein, GST-tagged Wheat Germ Human GST
LRP12-5161M Recombinant Mouse LRP12 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
LRP12-5161M-B Recombinant Mouse LRP12 Protein Pre-coupled Magnetic Beads HEK293 Mouse
LRP12-6014HF Recombinant Full Length Human LRP12 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 129 amino acids

    Involved Pathway

    LRP12 involved in several pathways and played different roles in them. We selected most pathways LRP12 participated on our site, such as Retinoid metabolism and transport,Signal Transduction,Visual phototransduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRP12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Visual phototransduction CNGA1,GRK7,METAP2A,RBP2A,RPE65B,BCO2L,STRA6,MYO7A,MYO7AA,RPE65A
    Signal Transduction FGFBP2,OPN4.1,OR52B4,CRABP1B,BOC,GPR65,OTUD7B,ADH8B,TRH,PRLH
    Retinoid metabolism and transport BCO2L,BCO2,LRP10,RBP1,APOA4A,APOC2,BCO2A,APOM,AKR1C6,AKR1C4

    Protein Function

    LRP12 has several biochemical functions, for example, low-density lipoprotein receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRP12 itself. We selected most functions LRP12 had, and list some proteins which have the same functions with LRP12. You can find most of the proteins on our site.

    Function Related Protein
    low-density lipoprotein receptor activity LRP6,VLDLR,CXCL16,LDLR,OLR1
    protein binding ABTB1,MTTP,CSTF2T,NEFL,FFAR2,HSPA5,HSP90AA1,RAB1A,LPP,NRBP1

    Interacting Protein

    LRP12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRP12 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRP12.

    ZFYVE9;GNB2L1;NMRK2;SNAPIN;ACTN2;MYOT

    Resources

    References

    • Katarzyna, MZ; Belaya, K; et al. Collagen Q - A potential target for autoantibodies in myasthenia gravis. JOURNAL OF THE NEUROLOGICAL SCIENCES 348:241-244(2015).
    • Gasperi, C; Melms, A; et al. Anti-agrin autoantibodies in myasthenia gravis. NEUROLOGY 82:1976-1983(2014).

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