LDHD
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Official Full Name
lactate dehydrogenase D -
Overview
The protein encoded by this gene belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. The similar protein in yeast has both D-lactate and D-glycerate dehydrogenase activities. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. -
Synonyms
LDHD;lactate dehydrogenase D;probable D-lactate dehydrogenase, mitochondrial;D lactate dehydrogenase;DLD;MGC57726;D-lactate dehydrogenase
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- His&GST
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LDHD-536H | Recombinant Human LDHD Protein, His-tagged | E.coli | Human | His | 159-507 aa | |
| LDHD-10246Z | Recombinant Zebrafish LDHD | Mammalian Cell | Zebrafish | His |
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| LDHD-1138H | Recombinant Human LDHD protein, His & GST-tagged | E.coli | Human | His&GST | Arg62~Ala265 |
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| LDHD-260H | Recombinant Human LDHD, GST-tagged | Wheat Germ | Human | GST |
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| LDHD-9024M | Recombinant Mouse LDHD Protein | Mammalian Cell | Mouse | His |
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| LDHD-979HCL | Recombinant Human LDHD cell lysate | Human | Non |
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| LDHD-5023M | Recombinant Mouse LDHD Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LDHD-5023M-B | Recombinant Mouse LDHD Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| LDHD-6971HF | Recombinant Full Length Human LDHD Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 507 amino acids |
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Involved Pathway
LDHD involved in several pathways and played different roles in them. We selected most pathways LDHD participated on our site, such as Metabolism of proteins,Mitochondrial protein import,Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with LDHD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyruvate metabolism | DLDH,ME1,PKMB,LDHBA,ACSS1,HAGH,ACSS2L,BRP44,SLC16A1,GRHPRA |
| Metabolism of proteins | EEF1B2,BCS1L,FKBP14,FURINB,IGFBP6,NOP56,TIMM8A,SEC63,ADAMTS4,TFG |
| Mitochondrial protein import | PMPCB,DNAJC19,GRPEL2,TOMM7,TOMM20,TIMM9,TIMM21,TIMM23,TOMM40,TOMM6 |
Protein Function
LDHD has several biochemical functions, for example, D-lactate dehydrogenase (cytochrome) activity,flavin adenine dinucleotide binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LDHD itself. We selected most functions LDHD had, and list some proteins which have the same functions with LDHD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| flavin adenine dinucleotide binding | ETFA,DUS3L,MAOB,ACADVL,XDH,FMO3,ACAD8,ACOX1,CYB5R3,CHDH |
| protein binding | MYL12A,KCTD15,KRTAP10-4,KATNA1,CRK,SNX1,PDCD5,TBX15,EPCAM,ETV6 |
Interacting Protein
LDHD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDHD here. Most of them are supplied by our site. Hope this information will be useful for your research of LDHD.
RPL22L1;CNOT8;METTL8;ZKSCAN1;MARK2;POLRMT;ZW10;SMNDC1;SOGA1;RPL30;MRPS21;SPAG1;TCEB2;MAP7D1;BCORL1;NIPBL;DHX30;ZC3HAV1;VRK2;SUGP1
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References
- Takahashi, H; Fujita, S; et al. Expression of heat shock protein 70 (HSP70) and EBV latent membrane protein 1 (LMP1) in Reed-Sternberg cells of Hodgkin's disease. ANALYTICAL CELLULAR PATHOLOGY 12:71-83(1996).
- Takahashi, H; Hideshima, K; et al. Immunophenotypes of Reed-Sternberg cells and their variants: A study of 68 cases of Hodgkin's disease. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 177:193-211(1995).
- OHSAWA, M; AOZASA, K; et al. IMMUNOREACTIVITIES OF REED-STERNBERG CELLS AND THEIR VARIANTS IN THE SEQUENTIAL BIOPSY OF HODGKINS-DISEASE. MODERN PATHOLOGY 6:457-462(1993).
- KINNEY, MC; GREER, JP; et al. ASSESSMENT OF LYMPHOCYTE DEPLETED HODGKINS-DISEASE, RETICULAR VARIANT, (LDHD-R) BY MONOCLONAL-ANTIBODIES REACTIVE IN PARAFFIN SECTIONS. LABORATORY INVESTIGATION 64:A75-A75(1991).
