KIF5B

  • Product List
  • Overview
  • Review / Q&A

  • Official Full Name

    kinesin family member 5B

  • Overview

    Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.

  • Synonyms

    KIF5B;kinesin family member 5B;KNS;KINH;KNS1;UKHC;HEL-S-61;kinesin-1 heavy chain;kinesin heavy chain;kinesin 1 (110-120kD);ubiquitous kinesin heavy chain;conventional kinesin heavy chain;epididymis secretory protein Li 61

Recombinant Proteins

  • Rat
  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • GST
  • Twin Strep
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
Kif5b-326R Recombinant Rat Kif5b protein, His-tagged E.coli Rat His Ile9~Lys226
KIF5B-377H Recombinant Human KIF5B, GST-tagged E.coli Human GST 662-782aa
Kif5b-262R Recombinant Rat Kif5b Protein, His-tagged E.coli Rat His Ile9~Lys226
KIF5B-317H Recombinant Human KIF5B protein, His-tagged E.coli Human His 662-782 aa
KIF5B-3259R Recombinant Rat KIF5B Protein Mammalian Cells Rat His
KIF5B-8648M Recombinant Mouse KIF5B Protein Mammalian Cells Mouse His
KIF5B-108H Recombinant Human kinesin family member 5B Protein, His&Twin Strep tagged E.coli Human His&Twin Strep 1-328aa
KIF5B-2915R Recombinant Rat KIF5B Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
KIF5B-2915R-B Recombinant Rat KIF5B Protein Pre-coupled Magnetic Beads HEK293 Rat
KIF5B-30173H Recombinant Human KIF5B protein, GST-tagged E.coli Human GST Glu662-Leu782
KIF5B-4820M Recombinant Mouse KIF5B Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
KIF5B-4820M-B Recombinant Mouse KIF5B Protein Pre-coupled Magnetic Beads HEK293 Mouse
KIF5B-954H Recombinant Human KIF5B protein, His-tagged E.coli Human His 1-431a.a.

Involved Pathway

KIF5B involved in several pathways and played different roles in them. We selected most pathways KIF5B participated on our site, such as Adaptive Immune System,Dopaminergic synapse,Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Insulin processing EXOC5,KIF5A,EXOC1,EXOC8,CPN1,SLC30A6,RAB27A,EXOC3,PCSK2,SLC30A8
Dopaminergic synapse GNAS,PRKACA,CALML3,GRIN2A,PPP2R1B,CREB3,DRD3,TH,GNG5,MAPK8
Insulin Signaling CAP1,ARHGAP33,STXBP3,MAPK6,MAPK4,MAP3K10,GRB14,STXBP2,STXBP3A,REG1A
Hemostasis MYB,GATA2A,KIF18A,CEACAM8,ZFPM2A,SERPINB8,KCNMB1,MAFGA,TREM1,PLEK
Immune System ARIH1L,DYNLL2,DDOST,HERC5,USP18,TAX1BP1,CYBB,DYNC1I2,UFL1,RNF41
Endocytosis WIPF2B,CSF1RA,CXCR4A,GRK7,BF1,MVB12A,RHOAA,CAV1,WAS,LDLRAP1B
Factors involved in megakaryocyte development and platelet production CABLES1,LRRC16A,GATA5,KIFAP3,ZFPM2A,KIF26A,HBBE2,DOCK9,KIF20A,PHF21A
Adaptive Immune System HUWE1,PAG1,AP2B1,IGHM,NRG4,CD200R4,UBE2U,RNF138,ERAP1,B2ML

Protein Function

KIF5B has several biochemical functions, for example, ATP binding,ATP-dependent microtubule motor activity, plus-end-directed,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF5B itself. We selected most functions KIF5B had, and list some proteins which have the same functions with KIF5B. You can find most of the proteins on our site.

Function Related Protein
protein binding TMEM8A,ERLIN2,CUTC,SLC7A1,INPP4B,CALB1,TIMM23,ZFPM2,FBP2,PTPN2
ATP binding PARS2,PLK3,UBE2G1,ROCK2,PEX1,PPP2R4,Aatk,ATP2A1,STK33,FDXACB1
microtubule binding NDEL1B,KIF18B,FAM154A,EML2,PLK1,MAPT,CCDC88A,PEX14,SNCA,MARK4
microtubule motor activity DYNLRB2,KIF4A,KIF2C,KIF25,KIF5AA,KIFC2,KIF20A,KIF23,DNHD1,KIFC3
ATP-dependent microtubule motor activity, plus-end-directed KIF17,KIF3B,KIF5AA,KIF20B,KIF1C,KIF5C,KIF1B,KIF14,KIF19,KIF3A

Interacting Protein

KIF5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF5B here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF5B.

YWHAZ;YWHAQ;YWHAB;YWHAG;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;BCAR3;VDAC1;NME2;SFN;VHL;RANBP2;Hap1

Resources

Gene Families

What Is Kinesins Gene Family

References

  • Hutarew, G; Hauser-Kronberger, C; et al. Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH. HISTOPATHOLOGY 65:398-407(2014).
  • Go, H; Jung, YJ; et al. Diagnostic method for the detection of KIF5B-RET transformation in lung adenocarcinoma. LUNG CANCER 82:44-50(2013).

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