KSR1
-
Official Full Name
kinase suppressor of ras 1 -
Overview
KSR1 (kinase supressor of Ras) was identified from a genetic screen in Drosophila and C. elegans as a component of the Ras signaling pathway. KSR1 has a putative carboxy-terminal kinase domain that lacks a key Lys residue for phospho-group transfer. Altho -
Synonyms
KSR1;kinase suppressor of ras 1;kinase suppressor of ras , KSR;RSU2;KSR
Recombinant Proteins
- Human
- Mouse
- Candida albicans
- Insect Cell
- Sf9 Insect Cell
- Mammalian Cell
- E. coli
- E.coli
- Wheat Germ
- HEK293
- Sf9 insect cells
- E.coli expression system
- GST
- His
- His&Fc&Avi
Involved Pathway
KSR1 involved in several pathways and played different roles in them. We selected most pathways KSR1 participated on our site, such as Ras signaling pathway,Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with KSR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tuberculosis | ITGB2,ARHGEF12,Cd209g,IL10RB,cgr2b,MRC2,FCGR1,BAX,LBP,HSPD1 |
| Ras signaling pathway | FGF8,FGF22,PRKACA,MAPK9,Kitl,PRKACG,RASA1,NGF,INS,FGF2 |
Protein Function
KSR1 has several biochemical functions, for example, ATP binding,MAP-kinase scaffold activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KSR1 itself. We selected most functions KSR1 had, and list some proteins which have the same functions with KSR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | SP2,PHYH,MORC4,ZNF74,ZNF35,GM12824,DDHD1,MUL1A,MLL1,ZFC3H1 |
| ATP binding | MYO7B,KIF5B,ATP2A2,YRK,EIF4A1A,NVL,ILF2,EPHA3,ABCB6A,RAF1B |
| mitogen-activated protein kinase kinase binding | ACE,RAF1,ARRB1,TRIB1,TAOK2,DLG1,PIN1,BRAF,TRIB3,TRIB2 |
| protein C-terminus binding | ERBB2,AGO2,ITPR1,SREBF2,CD2AP,PEX26,ARL6IP5,ATP1B1,NPAT,KCNJ11 |
| protein kinase activity | MYO3A,ABL2,ROCK2A,NEK4,MAP2K4,CAMK1GA,MAP3K14,FASTKD1,STK24,JAK2 |
| MAP-kinase scaffold activity | DUSP19,MAPK8IP2,SPAG9A,MAPK8IP3,CD36,JIP1,SPAG9 |
| protein binding | IMP4,CD244,AP5Z1,NOMO2,GCC1,UBE2U,CCKBR,RALB,HBXIP,ECT2 |
Interacting Protein
KSR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KSR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KSR1.
VRK2;MAP2K1;HSP90AB1;BRAF;BRAP;ARHGEF2;MAP2K2;tdh;YWHAB;PPP2CB;PPP2R2A;YWHAH;PPP2R5A;PPP2R5B;PPP2R5E;CALR
Resources
Related Services
Related Products
References
