KLRG1
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Official Full Name
killer cell lectin-like receptor subfamily G, member 1 -
Overview
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is comp -
Synonyms
KLRG1;killer cell lectin-like receptor subfamily G, member 1;killer cell lectin-like receptor subfamily G member 1;mast cell function-associated antigen 2F1;MAFA;2F1-Ag;MAFA-L;MGC123930
Recombinant Proteins
- Mouse
- Human
- Rat
- Mus musculus
- CHO
- HEK293
- Wheat Germ
- Mammalian Cell
- E.coli
- E. coli
- E.coli expression system
- Fc
- GST
- His
- Non
- His&Fc&Avi
- N-His&C-Myc
- His&SUMO
Involved Pathway
KLRG1 involved in several pathways and played different roles in them. We selected most pathways KLRG1 participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | AMICA1,CD300A,CD160,NCR3LG1,SIGLEC9,CLEC2H,CD200,CD300LF,CD226,CD300LD |
| Immune System | BTR02,IFI6,DCTN6,ART1,DEFB129,SLAMF6,ERAP1,SIGLEC7,USP18,LILRB1 |
| Adaptive Immune System | ASB7,CTSD,FBXO17,BLK,MGC174857,STUB1,KIF26A,UBA5,KIF2A,KIFAP3 |
Protein Function
KLRG1 has several biochemical functions, for example, carbohydrate binding,protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRG1 itself. We selected most functions KLRG1 had, and list some proteins which have the same functions with KLRG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SPRY2,CDK18,DEFB121,CRKL,CNTROB,MSLN,VPS35,SH3RF1,LY6H,NRCAM |
| receptor activity | KLRB1B,TLR2,VMN1R41,NLGN3,TMEM123,TNFRSF11A,ITGB1B,PAQR9,PAQR5B,GRIN3B |
| carbohydrate binding | GFPT1,Siglece,LGALSLB,GALNT18A,CLEC4F,NOMO1,ZP3,PKD1L3,SBP,MAN2C1 |
Interacting Protein
KLRG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRG1.
SYNE4;LEPROTL1
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References
- Broquet, A; Roquilly, A; et al. Depletion of Natural Killer Cells Increases Mice Susceptibility in a Pseudomonas aeruginosa Pneumonia Model. CRITICAL CARE MEDICINE 42:E441-E450(2014).
- Brando, C; Richardson, JH; et al. Phenotypic characterization of Plasmodium berghei responsive CD8+T cells after immunization with live sporozoites under chloroquine cover. MALARIA JOURNAL 13:-(2014).
