KLRF1

  • Official Full Name

    killer cell lectin-like receptor subfamily F, member 1

  • Overview

    KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK);cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 (PubMed 18922855)).

  • Synonyms

    KLRF1;killer cell lectin-like receptor subfamily F, member 1;killer cell lectin-like receptor subfamily F member 1;CLEC5C;NKp80;Activating coreceptor NKp80;C type lectin domain family 5 member C;killer cell lectin like receptor F1;Killer cell lectin like receptor subfamily F member 1;KLRF 1;Lectin like receptor F1;MGC119907;MGC119908;MGC119909;ML;OTTHUMP00000238675;OTTHUMP00000238676;OTTHUMP00000238678;lectin-like receptor F1;killer cell lectin-like receptor F1;C-type lectin domain family 5 member C

Recombinant Proteins

  • Human
  • Cynomolgus
  • Rhesus macaque
  • Mammalian Cells
  • HEK293
  • Human Cells
  • Wheat Germ
  • In Vitro Cell Free System
  • Fc
  • His
  • Non
  • His&Fc&Avi
  • Avi&His&Fc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
KLRF1-5672H Active Recombinant Human Killer Cell Lectin-Like Receptor Subfamily F, Member 1, Fc-tagged Mammalian Cells Human Fc 66-231 a.a.
KLRF1-1545C Active Recombinant Cynomolgus KLRF1 protein, hFc-tagged HEK293 Cynomolgus Fc Val66-Tyr231
KLRF1-2439R Recombinant Rhesus monkey KLRF1 Protein, His-tagged Mammalian Cells Rhesus macaque His
KLRF1-645C Recombinant Cynomolgus KLRF1 Protein, His-tagged Mammalian Cells Cynomolgus His
KLRF1-92C Recombinant cynomolgus KLRF1, Fc tagged Human Cells Cynomolgus His 66-231 a.a.
KLRF1-1034CCL Recombinant Cynomolgus KLRF1 cell lysate Human Cells Cynomolgus Non
KLRF1-113H Recombinant Human KLRF1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
KLRF1-113H-B Recombinant Human KLRF1 Protein Pre-coupled Magnetic Beads HEK293 Human
KLRF1-2260R Recombinant Rhesus Macaque KLRF1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
KLRF1-2260R-B Recombinant Rhesus Macaque KLRF1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
KLRF1-391C Recombinant Cynomolgus Monkey KLRF1 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus Avi&His&Fc
KLRF1-391C-B Recombinant Cynomolgus Monkey KLRF1 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
KLRF1-4908H Recombinant Human KLRF1 Protein, GST-tagged Wheat Germ Human GST
KLRF1-5774HF Recombinant Full Length Human KLRF1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 124 amino acids

    Involved Pathway

    KLRF1 involved in several pathways and played different roles in them. We selected most pathways KLRF1 participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System IGLC2,CLEC2B,CD300LG,IGKV1-5,LRRC41,FBXO3,KIF18A,DYNC1H1,KIR2DS2,EGF
    Immune System FCN2,KIFAP3,IFIT11,MAP3K8,CASPBL,SLAMF6,ARIH1L,IFI30,TRIM62,TREM1
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Mill2,TREML1,LILRB1,KLRB1B,CD300LF,SH2D1B,Siglece,CD200R2,CD200R4,SIGLEC8

    Protein Function

    KLRF1 has several biochemical functions, for example, MHC class I receptor activity,carbohydrate binding,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRF1 itself. We selected most functions KLRF1 had, and list some proteins which have the same functions with KLRF1. You can find most of the proteins on our site.

    Function Related Protein
    transmembrane signaling receptor activity NRXN1,CLEC2H,GABRQ,TLR9,GPR124,OR103-4,ANTXR1,LEPR,MARCO,KLRD1
    MHC class I receptor activity KIR3DS1,LILRB1,CD160,MR1
    carbohydrate binding UAP1,CD209B,FBXO6,LGALSL,FBXO2,GALNT5,ZP3,CLEC2D,PRG3,CNTN1

    Interacting Protein

    KLRF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRF1.

    Resources

    Research Area

    ITIM/ITAM Immunoreceptors and Related Molecules
    Natural Killer Cell (NK Cell)
    Natural Killer T (NKT) Cells
    C-type Lectin Family

    References

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