KLC2
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Official Full Name
kinesin light chain 2 -
Overview
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules.;Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric;ratio (Rahman et al., 1998 (PubMed 9624122)). -
Synonyms
KLC2;kinesin light chain 2;FLJ12387;KLC 2;KLC2_HUMAN;OTTHUMP00000165216;OTTHUMP00000165218;OTTHUMP00000165219;OTTHUMP00000165220
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- Insect Cells
- Mammalian cells
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
- His&GST
- Flag
Involved Pathway
KLC2 involved in several pathways and played different roles in them. We selected most pathways KLC2 participated on our site, such as Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Salmonella infection | IFNGR2,PFN2,CXCL8B.3,ACTG1,ACTB,CASP1,ARPC4L,MAPK10,PKN3,TLR4 |
Protein Function
KLC2 has several biochemical functions, for example, kinesin binding,microtubule motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLC2 itself. We selected most functions KLC2 had, and list some proteins which have the same functions with KLC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinesin binding | DISC1,GOLSYN,KLC3,AP1G1,KTN1,KCNC1,KIF18B,ATCAY,PLEKHM2,ARPC2 |
| protein binding | FOXRED2,ATXN2,FAM125B,BID,C9orf100,RBPMS2B,HER11,MAP2K2,CAMK2B,GNAQ |
| microtubule motor activity | DYNC1I1,DNAH5,DNAH11,KIFC3,KIF9,KIF26A,KIF3CB,KIF22,PROL1,DNAH14 |
Interacting Protein
KLC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLC2.
YWHAQ;YWHAG;YWHAZ;Hap1;SFN;S100A8;COIL;AIMP2;vgrG7;PIK3R3;Cep152;pi3p;KLC1;AP3D1;SOD1
Resources
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References
- Trejo, HE; Lecuona, E; et al. Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells. FASEB JOURNAL 24:374-382(2010).
