KIN
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Official Full Name
KIN, antigenic determinant of recA protein homolog (mouse) -
Overview
The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. -
Synonyms
KIN;KIN, antigenic determinant of recA protein homolog (mouse);antigenic determinant of recA protein (mouse) homolog;DNA/RNA-binding protein KIN17;KIN17;Binding to curved DNA;BTCD;HsKin17 protein;KIN antigenic determinant of recA protein homolog mouse;Kin17 protein;OTTHUMP00000019061;antigenic determinant of recA protein homolog
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
KIN involved in several pathways and played different roles in them. We selected most pathways KIN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KIN has several biochemical functions, for example, DNA binding,RNA binding,double-stranded DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIN itself. We selected most functions KIN had, and list some proteins which have the same functions with KIN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CEPT1,ZNF705A,ZNF200,NINL,CUBN,HBB-Y,ZFP598,HSCB,PRUNE2,ACO1 |
| RNA binding | EIF4G2A,RBM44,RPS4Y1,KHDRBS1A,DDX19B,RNMT,RBM18,KHNYN,DKC1,RBMY1B |
| double-stranded DNA binding | FBXO18,KLF6,TP63,XRCC3,GATA1A,NEIL3,EGFR,TEF,AFF3,SATB1 |
| DNA binding | TET3,ZNF582,HOXC3A,ZFP511,SALL3,POU6F1,PAX6B,LIN54,LIG1,KAT6B |
Interacting Protein
KIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIN here. Most of them are supplied by our site. Hope this information will be useful for your research of KIN.
lt_sv40;Bud13;Lgals3bp
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References
- Regina, A; Demeule, M; et al. ANG4043, a Novel Brain-Penetrant Peptide-mAb Conjugate, Is Efficacious against HER2-Positive Intracranial Tumors in Mice. MOLECULAR CANCER THERAPEUTICS 14:129-140(2015).
- Aubin, HJ; Berlin, I; et al. The Evolutionary Puzzle of Suicide. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 10:6873-6886(2013).
