KIF1A
-
Official Full Name
kinesin family member 1A -
Overview
The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] -
Synonyms
KIF1A;kinesin family member 1A;ATSV;MRD9;HSN2C;SPG30;UNC104;C2orf20;kinesin-like protein KIF1A;tmp_locus_27;microtubule-based motor KIF1A;unc-104- and KIF1A-related protein;axonal transporter of synaptic vesicles;kinesin, heavy chain, member 1A, homolog of mouse
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF1A-1121H | RecombinantHuman KIF1A Protein, His-tagged | E.coli | Human | His | 21-275 a.a. | |
| KIF1A-599M | Recombinant Mouse KIF1A Protein (1-361 aa), His-SUMO-tagged | E.coli | Mouse | His&SUMO | 1-361 aa |
|
Involved Pathway
KIF1A involved in several pathways and played different roles in them. We selected most pathways KIF1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KIF1A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by KIF1A itself. We selected most functions KIF1A had, and list some proteins which have the same functions with KIF1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
KIF1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF1A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF1A.
Resources
Related Services
Related Products
References
- Sgro, AE; Bajjalieh, SM; et al. Single-Axonal Organelle Analysis Method Reveals New Protein-Motor Associations. ACS CHEMICAL NEUROSCIENCE 4:277-284(2013).
- Zhang, LH; Gavin, T; et al. gamma-Diketone Axonopathy: Analyses of Cytoskeletal Motors and Highways in CNS Myelinated Axons. TOXICOLOGICAL SCIENCES 117:180-189(2010).
