JPH2
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Official Full Name
junctophilin 2 -
Overview
Junctophilin 2, also known as JPH2, is a protein which in humans is encoded by the JPH2 gene.Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. -
Synonyms
JPH2;junctophilin 2;JP2
Recombinant Proteins
- Rat
- Zebrafish
- Mouse
- Human
- Mammalian Cell
- HEK293
- Mammalian cells
- E.coli
- HEK293T
- His
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
JPH2 involved in several pathways and played different roles in them. We selected most pathways JPH2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with JPH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
JPH2 has several biochemical functions, for example, calcium-release channel activity,phosphatidic acid binding,phosphatidylinositol-3,4,5-trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JPH2 itself. We selected most functions JPH2 had, and list some proteins which have the same functions with JPH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-4-phosphate binding | SNX24,RS1,PRRC2B,ARFIP1,PLEKHA8,FAM21C,LANCL2,PLEKHF1,OSBPL8,GOLPH3L |
| phosphatidylinositol-3,5-bisphosphate binding | FAM21C,WIPI2,RAG2,KIF16B,RS1,CLVS1,MAPKAP1,D6WSU116E,WDR45L,SNX14 |
| phosphatidic acid binding | NRGN,MAPKAP1,PLCD1,SESTD1,PACSIN2,MARK1,RAPGEF6,UQCC3,MICALL1,COMMD1 |
| phosphatidylinositol-3,4,5-trisphosphate binding | RACGAP1,ANXA8,COMMD1,RS1,MAPKAP1,OGT,RAG2,CYTH3,MYO1G,D6WSU116E |
| calcium-release channel activity | RYR1,RYR3,RASA3,TRPV1,JPH3,RYR2 |
| phosphatidylinositol-3-phosphate binding | WIPI1,VPS36,SNX19,TECPR1,WIPI2,SH3PXD2B,RS1,ZFYVE26,ZFYVE19,SNX13 |
| phosphatidylserine binding | SYTL2,CD300A,GAP43,MARK1,OSBPL8,RPE65,PLCD1,ANXA13,RS1,AP1S2 |
| phosphatidylinositol-4,5-bisphosphate binding | SNX20,TTPA,SYTL2,FAM21C,ACTN2,TWF1,SNX21,ANXA8,RPH3A,PHLDA3 |
| phosphatidylinositol-5-phosphate binding | SH3PXD2B,FAM21C,RS1,PLEKHF1,D6WSU116E,PHLDA3,WIPI2,SNX3,LANCL2,SESTD1 |
Interacting Protein
JPH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JPH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of JPH2.
TRPC3;Trpc3;HTT;Ywhae
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References
- Weisleder, N; Takeshima, H; et al. Immuno-proteomic approach to excitation-contraction coupling in skeletal and cardiac muscle: Molecular insights revealed by the mitsugurnins. CELL CALCIUM 43:1-8(2008).
