Hist1h4f
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Official Full Name
HIST1H4F histone cluster 1, H4f [ Homo sapiens ] -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. -
Synonyms
histone cluster 1, H4f;4783;Ensembl:ENSG00000198327;histone H4;histone 1, H4f;H4 histone family, member C;H4;H4/c;H4FC
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST1H4F-13799H | Recombinant Human HIST1H4F, His-tagged | E.coli | Human | His | 1-103a.a. | |
| HIST1H4F-411H | Recombinant Human HIST1H4F Protein, His-tagged | E.coli | Human | His |
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| HIST1H4F-7689M | Recombinant Mouse HIST1H4F Protein | Mammalian Cell | Mouse | His |
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| HIST1H4F-5524HCL | Recombinant Human HIST1H4F 293 Cell Lysate | HEK293 | Human | Non |
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| HIST1H4F-4211M | Recombinant Mouse HIST1H4F Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIST1H4F-4211M-B | Recombinant Mouse HIST1H4F Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Hist1h4f involved in several pathways and played different roles in them. We selected most pathways Hist1h4f participated on our site, such as Alcoholism,Viral carcinogenesis,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hist1h4f were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral carcinogenesis | CASP8,PXN,HNRNPK,ACTN4,HLA-A,LYN,VAC14,HIST2H2BB,HIST2H4A,GTF2E2 |
| Systemic lupus erythematosus | H2AFB2,GM14483,HIST1H3H,IFNG,SNRPB,C2,C8A,GM5077,FCGR3,HIST1H4J |
| Alcoholism | SLC18A1,GNG12,GM14482,SHC3,GNG13,MAOB,HIST2H2AA4,GM6026,HIST1H2BF,KRAS |
Protein Function
Hist1h4f has several biochemical functions, for example, DNA binding,histone binding,histone demethylase activity (H4-K20 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by Hist1h4f itself. We selected most functions Hist1h4f had, and list some proteins which have the same functions with Hist1h4f. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | CDAN1,MIER1,NR1H3,ZFP507,TBX2A,ZIM3,POU3F3B,PHC1,HIST1H2AK,ZBTB41 |
| histone demethylase activity (H4-K20 specific) | PHF8,HIST1H4K,HIST1H4A,HIST1H4H,HIST1H4I,HIST1H4C,HIST1H4J,HIST1H4B,HIST4H4,HIST1H4L |
| poly(A) RNA binding | HSPA9,RPL4,EXOSC9,RCC2,NGRN,THUMPD1,RTF1,RBM5,BAG4,SNRPD1 |
| protein heterodimerization activity | FLOT1,BCL11A,SNX5,MAFGB,HIST1H2BK,MID2,MYOG,MYH7,SFRP5,APOA2 |
| histone binding | BRD1,TONSL,DNAJC2,CD1d1,ASF1B,HIST1H4K,PRKCBB,UHRF2,LEF1,HIST1H3F |
| protein binding | SYT1,COG5,HSF2,TBX22,METTL15,APBB1IP,ARSI,FRK,TTC3,GTF2A1L |
| protein domain specific binding | AKAP5,CALM,MTOR,SKI,HIST1H4J,RAB27A,MPP5,BHLHE40,FOXA1,DDX20 |
Interacting Protein
Hist1h4f has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hist1h4f here. Most of them are supplied by our site. Hope this information will be useful for your research of Hist1h4f.
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