HTR3B
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Official Full Name
5-hydroxytryptamine (serotonin) receptor 3B -
Overview
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of;the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a;hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not;functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional;features of this receptor. -
Synonyms
HTR3B;5-hydroxytryptamine (serotonin) receptor 3B;5-hydroxytryptamine receptor 3B;5 HT3B;5 HT3 B;5 HTR3B;5 hydroxytryptamine 3 receptor B subunit;5 hydroxytryptamine receptor 3B;5 hydroxytryptamine serotonin receptor 3B;5-HT3-B;5-HT3B;5-HTR3B;5-hydroxytryptamine 3 receptor B subunit;5-hydroxytryptamine serotonin receptor 3B;5HT3B_HUMAN;5HTR3B;Serotonin gated ion channel subunit;serotonin receptor 3B;serotonin-gated ion channel subunit
Recombinant Proteins
- Rat
- Mouse
- Human
- Mus musculus
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HTR3B-2966R | Recombinant Rat HTR3B Protein | Mammalian Cell | Rat | His |
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| HTR3B-7936M | Recombinant Mouse HTR3B Protein | Mammalian Cell | Mouse | His |
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| HTR3B-828HCL | Recombinant Human HTR3B cell lysate | Human | Non |
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| HTR3B-2621R | Recombinant Rat HTR3B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| HTR3B-2621R-B | Recombinant Rat HTR3B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| HTR3B-4377M | Recombinant Mouse HTR3B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HTR3B-4377M-B | Recombinant Mouse HTR3B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| HTR3B-5239H | Recombinant Human HTR3B Protein | Wheat Germ | Human | Non |
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| HTR3B-5693HF | Recombinant Full Length Human HTR3B Protein | In Vitro Cell Free System | Human | Full L. 172 amino acids |
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| RFL1854MF | Recombinant Full Length Mouse 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (22-437) |
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| RFL20927HF | Recombinant Full Length Human 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length of Mature Protein (22-441) |
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| RFL5589RF | Recombinant Full Length Rat 5-Hydroxytryptamine Receptor 3B(Htr3B) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length of Mature Protein (22-437) |
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Involved Pathway
HTR3B involved in several pathways and played different roles in them. We selected most pathways HTR3B participated on our site, such as Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Serotonergic synapse | PRKACA,PLCB1,GNB4,PTGS2,GNG11,RAF1,NRAS,MAPK1,GNB2,PLA2G4C |
Protein Function
HTR3B has several biochemical functions, for example, NOT contributes_to acetylcholine binding,NOT contributes_to acetylcholine receptor activity,NOT contributes_to acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR3B itself. We selected most functions HTR3B had, and list some proteins which have the same functions with HTR3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT contributes_to acetylcholine receptor activity | HTR3C,HTR3A,HTR3E |
| serotonin receptor activity | HTR4,HTR2C,HTR7,HTR1B,HTR1A,HTR1AA,HTR5A,HTR3E,HTR1F,HTR1AB |
| ion channel activity | GRIN2A,CHRNA4B,TRPC2B,FXYD6L,CNGA5,TRPN1,TRPV5,GJD3,P2RX3A,KCNK3 |
| NOT contributes_to acetylcholine-activated cation-selective channel activity | HTR3A,HTR3C,HTR3E |
| NOT contributes_to acetylcholine binding | HTR3C,HTR3E,HTR3A |
| serotonin-activated cation-selective channel activity | HTR3E,HTR3C,HTR3A |
Interacting Protein
HTR3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HTR3B here. Most of them are supplied by our site. Hope this information will be useful for your research of HTR3B.
HTR3A
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