HPR
-
Official Full Name
haptoglobin-related protein -
Overview
This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. -
Synonyms
HPR;haptoglobin-related protein;Haptoglobin related locus;haptoglobin related protein;HP;Haptoglobin-related locus;A-259H10.2
Recombinant Proteins
- Bacillus subtilis
- Human
- Mouse
- E. coli or Yeast
- E.coli
- HEK293
- HEK293T
- Mammalian cells
- His
- His&T7
- His&Fc&Avi
- Myc&DDK
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HPR-0053B | Recombinant Bacillus subtilis HPR protein, His-tagged | E. coli or Yeast | Bacillus subtilis | His |
|
|
| HPR-2092H | Recombinant Human HPR protein, His & T7-tagged | E.coli | Human | His&T7 | Asn70~Val332 |
|
| HPR-484H | Recombinant Human haptoglobin-related protein, His-tagged | E.coli | Human | His | 20-348 a.a. |
|
| HPR-5085H | Recombinant Human HPR, His-tagged | E.coli | Human | His |
|
|
| HPR-1095H | Recombinant Human HPR Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| HPR-1095H-B | Recombinant Human HPR Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| HPR-1890H | Recombinant Human HPR Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
|
| HPR-2697M | Recombinant Mouse HPR Protein, His-tagged | E.coli | Mouse | His | Val19-Asn347 |
|
| HPR-4302H | Recombinant Human HPR Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
|
| HPR-509HFL | Recombinant Full Length Human HPR Protein, C-Flag-tagged | Mammalian cells | Human | Flag | Full L. |
|
Involved Pathway
HPR involved in several pathways and played different roles in them. We selected most pathways HPR participated on our site, such as African trypanosomiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| African trypanosomiasis | SELE,IFNG,PRKCB,HBA2,IL6,HBA1,HBB,PRKCA,ICAM1,FASLG |
Protein Function
HPR has several biochemical functions, for example, hemoglobin binding,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HPR itself. We selected most functions HPR had, and list some proteins which have the same functions with HPR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hemoglobin binding | LRP2,HBB,AHSP,HP,CUBN |
| serine-type endopeptidase activity | CTSC,PRSS58,PRSS52,HGF,TPSAB1,TMPRSS4B,TMPRSS7,MCPT9,CELA1,KLK1B8 |
Interacting Protein
HPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HPR here. Most of them are supplied by our site. Hope this information will be useful for your research of HPR.
d-mannose
Resources
Related Services
Related Products
References
- Fraser, JE; Watanabe, S; et al. A Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection. JOURNAL OF INFECTIOUS DISEASES 210:1780-1791(2014).
- Fourrier, M; Lester, K; et al. Deletions in the highly polymorphic region (HPR) of infectious salmon anaemia virus HPR0 haemagglutinin-esterase enhance viral fusion and influence the interaction with the fusion protein. JOURNAL OF GENERAL VIROLOGY 95:1015-1024(2014).
