HOXB3
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Official Full Name
homeobox B3 -
Overview
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). -
Synonyms
HOXB3;homeobox B3;homeo box B3 , HOX2, HOX2G;homeobox protein Hox-B3;Homeo box 2G;Homeo box B3;Homeobox protein Hox-2.7;Homeobox protein Hox-2G;Homeobox protein HoxB3;Hox 2.7;HOX 2G;HOX2;Hox2.7;HOX2G;HXB3_HUMAN;Hox-2.7
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXB3-28511TH | Recombinant Human HOXB3 | Wheat Germ | Human | Non | 99 amino acids |
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| HOXB3-4959H | Recombinant Human HOXB3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXB3-6308C | Recombinant Chicken HOXB3 | Mammalian Cell | Chicken | His |
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| HOXB3-3717HF | Recombinant Full Length Human HOXB3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 431 amino acids |
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Involved Pathway
HOXB3 involved in several pathways and played different roles in them. We selected most pathways HOXB3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HOXB3 has several biochemical functions, for example, RNA polymerase II core promoter sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXB3 itself. We selected most functions HOXB3 had, and list some proteins which have the same functions with HOXB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | EOMESA,ZNF567,PHOX2A,NFIL3-2,ZFY2,KDM1A,T,PPARAB,CNBP,ZNF263 |
| RNA polymerase II core promoter sequence-specific DNA binding | TP53,ZNF335,MTF1,HNF4A,SMYD3,HEYL,IRF7,ZFPM1,SOX11,GATA1 |
Interacting Protein
HOXB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXB3.
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