HOOK1
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Official Full Name
hook homolog 1 -
Overview
This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. -
Synonyms
HOOK1;hook homolog 1 (Drosophila);protein Hook homolog 1;HK1;hHK1;h-hook1;MGC10642
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOOK1-1680C | Recombinant Chicken HOOK1 | Mammalian Cell | Chicken | His |
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| HOOK1-4222Z | Recombinant Zebrafish HOOK1 | Mammalian Cell | Zebrafish | His |
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| HOOK1-4928H | Recombinant Human HOOK1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOOK1-5435HCL | Recombinant Human HOOK1 293 Cell Lysate | HEK293 | Human | Non |
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| Hook1-3428M | Recombinant Mouse Hook1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HOOK1-3695HF | Recombinant Full Length Human HOOK1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 728 amino acids |
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Involved Pathway
HOOK1 involved in several pathways and played different roles in them. We selected most pathways HOOK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HOOK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
HOOK1 has several biochemical functions, for example, actin binding,identical protein binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOOK1 itself. We selected most functions HOOK1 had, and list some proteins which have the same functions with HOOK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | BAX,PIK3AP1,HAPLN2,KCNJ10,FBXW7,SH3GL3,SYNE1,SYT9,GRB7,MTSS1 |
| protein binding | ADRB1,PVRL4,C22orf39,DTX3,PPIL3,SESN2,ARIH1,SESTD1, Cd79b,TSSK1 |
| actin binding | SPIRE1,TNS1,AVIL,SPTB,NF2B,CFL2L,MAEA,MSRB1A,EZRB,ALDOA |
Interacting Protein
HOOK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOOK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOOK1.
AKTIP;ZNF785;USP2;CDK4;LMO2;SYCE1;TBC1D7
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References
- Richardson, SCW; Winistorfer, SC; et al. Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. MOLECULAR BIOLOGY OF THE CELL 15:1197-1210(2004).
