HNRNPM
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Official Full Name
heterogeneous nuclear ribonucleoprotein M -
Overview
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. -
Synonyms
HNRNPM;heterogeneous nuclear ribonucleoprotein M;HNRPM, NAGR1;CEA receptor;CEAR;HNRNPM4;HNRPM4;HTGR1;hnRNA-binding protein M4;N-acetylglucosamine receptor 1;heterogenous nuclear ribonucleoprotein M4;HNRPM;NAGR1;hnRNP M;DKFZp547H118
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- His&SUMO
- GST
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HNRNPM-5432H |
Recombinant Human HNRNPM protein, His-tagged
|
E.coli | Human | His | ||
| HNRNPM-1244H | Recombinant Human HNRNPM Protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 2-730 a.a. |
|
| HNRNPM-2621C | Recombinant Chicken HNRNPM | Mammalian Cell | Chicken | His |
|
|
| HNRNPM-5438H | Recombinant Human HNRNPM protein, GST-tagged | Wheat Germ | Human | GST | 1-730 a.a. |
|
| HNRNPM-8171Z | Recombinant Zebrafish HNRNPM | Mammalian Cell | Zebrafish | His |
|
|
| HNRNPM-5440HCL | Recombinant Human HNRNPM 293 Cell Lysate | HEK293 | Human | Non |
|
|
| HNRNPM-728HF | Recombinant Full Length Human HNRNPM Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 730 amino acids |
|
Involved Pathway
HNRNPM involved in several pathways and played different roles in them. We selected most pathways HNRNPM participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | HSPA1A,SF3B2,TXNL4A,MAGOHB,SNRPB,SNW1,HSP70L,DHX15,PLRG1,SRSF5B |
Protein Function
HNRNPM has several biochemical functions, for example, RNA binding,antigen binding,nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPM itself. We selected most functions HNRNPM had, and list some proteins which have the same functions with HNRNPM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein domain specific binding | IRS2,CACNB2,EHD2,HIST1H4K,EZR,CBX3,PTPN11,AKAP5,DDX6,TUBB |
| nucleotide binding | RBMS3,PDPK1A,TINAG,CNOT4B,CDC42L2,ABCB3L1,MOV10B.2,TRMT2A,PTBP1A,RBM4.3 |
| RNA binding | HNRNPL2,WRAP53,MOV10B.1,CPEB1B,KHDC1,HNRNPAB,U2SURP,DCP2,DDX53,RPL14 |
| protein binding | RTN4RL1B,LDHD,C11orf65,SRRT,ILK,UBE2H,NRP1B,GOLPH3,HTR3E,CIT |
| poly(A) RNA binding | ZC3H14,MRPL21,YARS2,EMG1,MKRN2,NAT10,TARDBP,MRPL1,RBBP6,CLTC |
| antigen binding | IgG3,CD40,LILRA3,LILRA1,TGFB1,Ighg2a,MHC1UKA,LCK,LAG3,TSPAN4 |
Interacting Protein
HNRNPM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPM here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPM.
LMO2;CDC5L;PLRG1;4005;HNRNPF
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