HKDC1

  • Official Full Name

    hexokinase domain containing 1
  • Synonyms

    HKDC1;hexokinase domain containing 1;FLJ22761;FLJ37767;Q2TB90;MGC125688;OTTHUMP00000019718;putative hexokinase HKDC1;Hexokinase domain-containing protein 1;EC 2.7.1;EC 2.7.1.1

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • HEK293
  • Wheat Germ
  • Mammalian Cell
  • HEK293T
  • Myc&DDK
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
HKDC1-315H Recombinant Human HKDC1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
HKDC1-4828H Recombinant Human HKDC1 Protein, GST-tagged Wheat Germ Human GST
HKDC1-6544Z Recombinant Zebrafish HKDC1 Mammalian Cell Zebrafish His
HKDC1-7715M Recombinant Mouse HKDC1 Protein Mammalian Cell Mouse His
HKDC1-795HCL Recombinant Human HKDC1 cell lysate Human Non
HKDC1-1345H Recombinant Human HKDC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Hkdc1-3408M Recombinant Mouse Hkdc1 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
HKDC1-4230M Recombinant Mouse HKDC1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
HKDC1-4230M-B Recombinant Mouse HKDC1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    HKDC1 involved in several pathways and played different roles in them. We selected most pathways HKDC1 participated on our site, such as Glycolysis / Gluconeogenesis,Fructose and mannose metabolism,Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HKDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways TKT,TK2,MAN2A1,ALAD,NADSYN1,MGAT1A,CPS1,G6PDX,ALDH6A1,CTPS2
    Starch and sucrose metabolism UGT1A1,UGT1A4,UGT1A9,SI,GBE1,AMY2A3,GPIB,UGT1AB,PYGL,UGT2A2
    Galactose metabolism AKR1B8,UGP2B,PFKMA,G6PC2,GAA,aLA,PFKL,SI,UGP2,GALE
    Central carbon metabolism in cancer SCO2,TP53,FGFR3,PFKM,SLC2A2,PFKP,HK2,KIT,PIK3CD,FLT3
    Type II diabetes mellitus ADIPOQ,MTOR,SOCS1,PIK3R2,PIK3CG,MAPK8,PDX1,PRKCD,INS-IGF2,PIK3CD
    HIF- signaling pathway TLR4,IGF1R,ENO3,TF,RELA,RPS6KB1,PLCG1,PFKFB3,GAPDH,PIK3R1
    Insulin signaling pathway HRAS,PRKAB1B,PRKAG1,FASN,PRKACA,INS2,BAD,PIK3R5,IRS1,MAP2K1
    Butirosin and neomycin biosynthesis HK2,HK3,HK1
    Carbon metabolism OGDHL,GLUD1A,PC,PDHA1A,PHGDH,PFKP,AMT,FH,ENO1A,TKTL2

    Protein Function

    HKDC1 has several biochemical functions, for example, ATP binding,fructokinase activity,glucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HKDC1 itself. We selected most functions HKDC1 had, and list some proteins which have the same functions with HKDC1. You can find most of the proteins on our site.

    Function Related Protein
    mannokinase activity HK3,HK2,HK1
    fructokinase activity HK1,HK2,HK3
    glucose binding G6PD,SLC2A8,HK1,SLC2A3,HK3,HK2,PYGL,GYS1,G6PDX,UGP2
    ATP binding CKMB,SUCLG1,HELB,KIT,DDX46,ACSF2,ABCA3,ABCD4,UBA7,NPR1A
    glucokinase activity HK1,HK3,HK2

    Interacting Protein

    HKDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HKDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HKDC1.

    ssrna_ug

    Resources

    References

    • Hu, CJ; Song, G; et al. Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays. MOLECULAR & CELLULAR PROTEOMICS 11:669-680(2012).
    • Hashimoto, M; Wilson, JE; et al. Kinetic and regulatory properties of HKI+, a modified form of the type I isozyme of mammalian hexokinase in which interactions between the N- and C-terminal halves have been disrupted. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 399:109-115(2002).

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