HIST1H2BJ
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Official Full Name
histone cluster 1, H2bj -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. -
Synonyms
HIST1H2BJ;histone cluster 1, H2bj;H2B histone family, member R , H2BFR, histone 1, H2bj;histone H2B type 1-J;H2B/r;H2B histone family member R;H2B1J_HUMAN;H2BFR;Histone 1 H2bj;Histone cluster 1 H2bj;Histone H2B.1;Histone H2B.r;histone 1, H2bj;H2B histone family, member R
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Mammalian Cell
- HEK293
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HIST1H2BJ-2097R | Recombinant Rhesus monkey HIST1H2BJ Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| HIST1H2BJ-438H | Recombinant Human HIST1H2BJ Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| HIST1H2BJ-7668M | Recombinant Mouse HIST1H2BJ Protein | Mammalian Cell | Mouse | His |
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| HIST1H2BJ-1918R | Recombinant Rhesus Macaque HIST1H2BJ Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| HIST1H2BJ-1918R-B | Recombinant Rhesus Macaque HIST1H2BJ Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| HIST1H2BJ-4195M | Recombinant Mouse HIST1H2BJ Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HIST1H2BJ-4195M-B | Recombinant Mouse HIST1H2BJ Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HIST1H2BJ involved in several pathways and played different roles in them. We selected most pathways HIST1H2BJ participated on our site, such as Alcoholism,Viral carcinogenesis,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H2BJ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Systemic lupus erythematosus | HLA-DOA,HIST2H2AA2,HIST1H2AL,C1RA,HIST1H2AJ,C6,HLA-DPB1,HIST1H2AF,C1S,HIST1H2BP |
| Alcoholism | GM14482,GNG3,GM6026,HIST1H2BQ,NRAS,HIST1H2AO,HIST1H3I,HIST1H4N,GNG10,H2AFV |
| Viral carcinogenesis | RBL2,PKM,CCNA2,HIST1H2BC,CREB5,PIK3CD,HIST1H2BQ,VAC14,TRAF2,PKM2 |
Protein Function
HIST1H2BJ has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H2BJ itself. We selected most functions HIST1H2BJ had, and list some proteins which have the same functions with HIST1H2BJ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | KDM5C,POU3F2B,IFIH1,NR4A2A,SLC2A4RG,ESRRA,POLN,OTX1A,FOXO1B,MTERFD1 |
Interacting Protein
HIST1H2BJ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H2BJ here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H2BJ.
Uhrf1;Ywhae;Hsd3b4
Resources
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References
- Roth, S; Franken, P; et al. Generation and characterization of an inducible transgenic model for studying mouse esophageal biology. BMC DEVELOPMENTAL BIOLOGY 12:-(2012).
- Kitazawa, M; Ohnuma, T; et al. No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 159B:456-464(2012).
- Loe-Mie, Y; Lepagnol-Bestel, AM; et al. SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution. HUMAN MOLECULAR GENETICS 19:2841-2857(2010).
- Roth, S; Franken, P; et al. Generation of a Tightly Regulated Doxycycline-Inducible Model for Studying Mouse Intestinal Biology. GENESIS 47:7-13(2009).
