HIST1H2AA
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Official Full Name
histone cluster 1, H2aa -
Overview
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in;eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of;each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the;interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.;This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a;palindromic termination element.
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HIS
- His
- GST
- Non
- His&GST
- His&Fc&Avi
Involved Pathway
HIST1H2AA involved in several pathways and played different roles in them. We selected most pathways HIST1H2AA participated on our site, such as Alcoholism,Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H2AA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alcoholism | HIST2H2BE,HIST2H2AA4,HIST2H3C2,CALM4,HIST1H4H,HIST1H2AN,HIST1H2BI,HIST3H3,HDAC7A,H2AFY2 |
| Systemic lupus erythematosus | H3F3A,HIST2H3C1,HIST1H4N,HLA-DQA2,HIST2H4,SNRPD1,H2AFB1,GM14477,HIST1H4B,HIST1H3I |
Protein Function
HIST1H2AA has several biochemical functions, for example, DNA binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H2AA itself. We selected most functions HIST1H2AA had, and list some proteins which have the same functions with HIST1H2AA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | IL12B,H2AFY2,ANO2,SLC3A1,ITGB1A,PIK3R1,SPTAN1,BOKA,BNIP3L,ARNT2 |
| DNA binding | CSDC2,ETV5,RARGB,MLLT1,BRIP1,SUPT6H,ZNF184,HIVEP3,MIER1,POT1A |
Interacting Protein
HIST1H2AA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H2AA here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H2AA.
BRD7;EGFR;FN1;UBC;EIF4A3;MAGOH;SFMBT1
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