HEMGN
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Official Full Name
hemogen -
Overview
Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). -
Synonyms
HEMGN;hemogen;NDR;EDAG;CT155;EDAG-1;hemopoietic gene protein;negative differentiation regulator protein;erythroid differentiation-associated gene protein
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
HEMGN-13733H | Recombinant Human HEMGN, GST-tagged | E.coli | Human | GST | 139-483a.a. | |
HEMGN-2824R | Recombinant Rat HEMGN Protein | Mammalian Cell | Rat | His | ||
HEMGN-4686H | Recombinant Human HEMGN Protein, GST-tagged | Wheat Germ | Human | GST | ||
HEMGN-7571M | Recombinant Mouse HEMGN Protein | Mammalian Cell | Mouse | His | ||
HEMGN-5588HCL | Recombinant Human HEMGN 293 Cell Lysate | HEK293 | Human | Non | ||
HEMGN-2479R | Recombinant Rat HEMGN Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi | ||
HEMGN-2479R-B | Recombinant Rat HEMGN Protein Pre-coupled Magnetic Beads | HEK293 | Rat | |||
HEMGN-3475HF | Recombinant Full Length Human HEMGN Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 484 amino acids | |
HEMGN-4121M | Recombinant Mouse HEMGN Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi | ||
HEMGN-4121M-B | Recombinant Mouse HEMGN Protein Pre-coupled Magnetic Beads | HEK293 | Mouse | |||
HEMGN-4651H | Recombinant Human HEMGN Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
Involved Pathway
HEMGN involved in several pathways and played different roles in them. We selected most pathways HEMGN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HEMGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
HEMGN has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HEMGN itself. We selected most functions HEMGN had, and list some proteins which have the same functions with HEMGN. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
protein binding | TNFSF12,TUB,OTUD7B,NME1,CD40,NOL3,PHOSPHO2,RAD9A,NCK1,HOOK3 |
Interacting Protein
HEMGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HEMGN here. Most of them are supplied by our site. Hope this information will be useful for your research of HEMGN.
NPM1;CTBP1;AURKA;BUB1;TLR2;BCL10;EGFR;NRAS;KRAS;ODC1;CDH1;SRC;MCC
Resources
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References
- Lambeth, LS; Raymond, CS; et al. Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads. DEVELOPMENTAL BIOLOGY 389:160-172(2014).
- Wei, M; Shi, R; et al. The over-expression of aquaporin-1 alters erythroid gene expression in human erythroleukemia K562 cells. TUMOR BIOLOGY 36:291-302(2015).