HELLS
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Official Full Name
helicase, lymphoid-specific -
Overview
HELLS, or LSH1, is a lymphoid-specific helicase thought to be involved in cellular proliferation and leukemogenesis. It is believed to be a chromatin remodeler and is required for DNMT1-mediated methylation maintenance and DNMT3A/DNMT3B-mediated de novo m -
Synonyms
HELLS;helicase, lymphoid-specific;lymphoid-specific helicase;LSH;Nbla10143;PASG;proliferation associated SNF2 like protein;SMARCA6;SWI/SNF2 related;matrix associated;actin dependent regulator of chromatin;subfamily A;member 6;proliferation-as
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HELLS-13730H | Recombinant Human HELLS, GST-tagged | E.coli | Human | GST | 1-348a.a. | |
| HELLS-2064R | Recombinant Rhesus monkey HELLS Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| HELLS-31195TH | Recombinant Human HELLS | Wheat Germ | Human | Non | 348 amino acids |
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| HELLS-3472Z | Recombinant Zebrafish HELLS | Mammalian Cell | Zebrafish | His |
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| HELLS-4683H | Recombinant Human HELLS Protein, GST-tagged | Wheat Germ | Human | GST |
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| HELLS-7567M | Recombinant Mouse HELLS Protein | Mammalian Cell | Mouse | His |
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| HELLS-5589HCL | Recombinant Human HELLS 293 Cell Lysate | HEK293 | Human | Non |
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| Hells-1109M | Recombinant Mouse Hells Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| HELLS-11HFL | Recombinant Full Length Human HELLS Protein, C-Myc/DDK-tagged | HEK293T | Human | Myc&DDK | Full L. |
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| HELLS-1885R | Recombinant Rhesus Macaque HELLS Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| HELLS-1885R-B | Recombinant Rhesus Macaque HELLS Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| HELLS-224HF | Recombinant Full Length Human HELLS Protein | In Vitro Cell Free System | Human | Full L. 348 amino acids |
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| HELLS-3472HF | Recombinant Full Length Human HELLS Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 348 amino acids |
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| HELLS-4117M | Recombinant Mouse HELLS Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| HELLS-4117M-B | Recombinant Mouse HELLS Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
HELLS involved in several pathways and played different roles in them. We selected most pathways HELLS participated on our site, such as Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HELLS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Apoptosis | CASP3B,TRAF2,CASP2,PIK3R1,TNFRSFA,TNFRSF10D,PIK3R3B,CASP6L1,PIK3CD,NTRK1 |
Protein Function
HELLS has several biochemical functions, for example, ATP binding,helicase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HELLS itself. We selected most functions HELLS had, and list some proteins which have the same functions with HELLS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TUBB4A,MAGEA3,FAM131C,FIGNL1,TTK,TFAP2A,HIST1H2BE,ZBTB26,C16orf45,MEIOB |
| helicase activity | DDX19,PIF1,IFIH1,DDX51,DHX36,GTF2F2,YTHDC2,ZRANB3,CHD1L,NAV2 |
| ATP binding | MAP2K2A,AK8,CCT8L2,EIF4A3,EPHB4A,MB21D1,MAP3K10,MCM9,XRCC5,MTHFS |
Interacting Protein
HELLS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HELLS here. Most of them are supplied by our site. Hope this information will be useful for your research of HELLS.
MYC;E2F3;CIAO1;MAGEA6;yidC;SNW1;LRRK2;CDC5L
Resources
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References
- Schaufuss, P; Steller, U; et al. Passive immunisation - an old method newly discovered. TIERAERZTLICHE UMSCHAU 64:132-138(2009).
- Jakel, A; Plested, JS; et al. Naturally-occurring human serum antibodies to inner core lipopolysaccharide epitopes of Neisseria meningitidis protect against invasive meningococcal disease caused by isolates displaying homologous inner core structures. VACCINE 26:6655-6663(2008).
