HCRTR2
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Official Full Name
hypocretin (orexin) receptor 2 -
Overview
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. -
Synonyms
HCRTR2;hypocretin (orexin) receptor 2;orexin receptor type 2;OX2R;Hypocretin receptor 2;Hypocretin receptor type 2;Orexin receptor 2;Ox-2-R;Ox2-R;OX2R_HUMAN;OTTHUMP00000017762
Recombinant Proteins
- Chicken
- Rat
- Human
- Zebrafish
- Mouse
- Dog
- Mus musculus
- Mammalian Cell
- Wheat Germ
- Insect Cell
- HEK293
- Yeast
- E.coli expression system
- His
- GST
- Non
- His&Flag
- His&Fc&Avi
Involved Pathway
HCRTR2 involved in several pathways and played different roles in them. We selected most pathways HCRTR2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCRTR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | DRD2L,F2,CHRNA10,GALR3,TRY,ADORA3,OPRM1,TACR1B,TAAR12G,EDNRB2 |
Protein Function
HCRTR2 has several biochemical functions, for example, neuropeptide receptor activity,orexin receptor activity,peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HCRTR2 itself. We selected most functions HCRTR2 had, and list some proteins which have the same functions with HCRTR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide hormone binding | INHBA,GIPR,MC3R,GHR,RXFP2,AVPR1A,GHRHR,AGTR2,PRLR,GHSR |
| neuropeptide receptor activity | HCRTR1,NPFFR1L2,GPR139,NPSR1,NPFFR2.1,MCHR1,NPBWR1,PRLHR,SORCS1,KISS1R |
| peptide binding | LNPEP,CRHBP,GPR37,PCSK5,H2-Q10,FNTB,PPIA,ERCC3,LTA4H,ADNP |
| orexin receptor activity | HCRTR1 |
Interacting Protein
HCRTR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCRTR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCRTR2.
Resources
Research Area
Neurotransmitter G Protein-Coupled ReceptorsPeptide Hormone G Protein-Coupled Receptors
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References
