HBD
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Official Full Name
HBD hemoglobin, delta [ Homo sapiens ] -
Overview
The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5-epsilon--Ggamma--Agamma--delta--beta-3. Mutations in the delta-globin gene are associated with beta-thalassemia. -
Synonyms
hemoglobin, delta;4829;Ensembl:ENSG00000223609;hemoglobin subunit delta;delta globin;delta-globin chain;hemoglobin delta chain
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HBD-13680H | Recombinant Human HBD, GST-tagged | E.coli | Human | GST | 1-147a.a. | |
| HBD-7861H | Recombinant Human HBD protein, His & GST-tagged | E.coli | Human | His&GST | Met1~Ala143 |
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| HBD-5621HCL | Recombinant Human HBD 293 Cell Lysate | HEK293 | Human | Non |
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| HBD-1060H | Recombinant Human HBD Protein, His-tagged | E.coli | Human | His |
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| HBD-2443H | Recombinant Human HBD Protein (Met1-Ala143), N-GST tagged | E.coli | Human | GST | Met1-Ala143 |
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| HBD-4296H | Recombinant Human HBD protein, His-GST-tagged | E.coli | Human | His&GST | 2-147aa |
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Involved Pathway
HBD involved in several pathways and played different roles in them. We selected most pathways HBD participated on our site, such as Factors involved in megakaryocyte development and platelet production,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HBD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hemostasis | BA2,KIF4A,PRTN3,CD84,SERPINF2B,PDE10A,DGKB,SLC7A8A,PRKCHB,ATP2B3A |
| Factors involved in megakaryocyte development and platelet production | ZFPM1,NFE2,HBBE2,KIF2C,BA1,KIF2B,KIF15,RACGAP1,KIFAP3,KIF3C |
Protein Function
HBD has several biochemical functions, for example, heme binding,iron ion binding,oxygen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HBD itself. We selected most functions HBD had, and list some proteins which have the same functions with HBD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron ion binding | CYP2C8,TYW1,CYP2W1,CYP2C9,ALOX5,EGLN1B,CYP2V1,CYP2D9,CYP2P10,CYP4A14 |
| protein binding | TPX2,MED9,HSPB2,DAO,SMARCA5,KCNJ5,NBR1,KAT8,MAP1B,FCRL2 |
| oxygen transporter activity | HBAD,HBE1,HBAE1,HBE,HBA2,HBA1,HBAE3,HBBE1.1,HBB-Y,CYGB1 |
| oxygen binding | CYP2P9,CYP19A1,CYGB,CYP17A1,CYP2A6,CYP3A5,CYP2D6,HBB,HBG2,CYP2X7 |
| heme binding | NOS1,CYP2A7,CYP19A1B,CYP4Z1,CYP2K17,HBE1,CYP4F18,CYP2AA8,DGCR8,CYP4B1 |
Interacting Protein
HBD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HBD here. Most of them are supplied by our site. Hope this information will be useful for your research of HBD.
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