HAL
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Official Full Name
histidine ammonia-lyase -
Overview
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative;deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is;characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript;variants encoding different isoforms have been found for this gene. -
Synonyms
HAL;histidine ammonia-lyase;HIS;hutH 1;HAL protein;histidase;Histidine ammonia lyase;HSTD;HutH;OTTHUMP00000243562;OTTHUMP00000243565
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Chicken
- Mouse
- HEK293
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293T
- In Vitro Cell Free System
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
HAL involved in several pathways and played different roles in them. We selected most pathways HAL participated on our site, such as Histidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CYP2R1,INPP4B,NT5C1B-RDH14,DGAT2,DCT,AMPD3B,CYP2P8,UXS1,TKTL1,INPP1 |
| Histidine metabolism | ALDH7A1,HNMT,UROC1,ALDH1A3,CNDP1,ALDH3A1,ABP1,ALDH3B2,ALDH2.2,FTCD |
Protein Function
HAL has several biochemical functions, for example, histidine ammonia-lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HAL itself. We selected most functions HAL had, and list some proteins which have the same functions with HAL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
HAL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAL here. Most of them are supplied by our site. Hope this information will be useful for your research of HAL.
STK4
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References
- Kugler, J; Wilke, S; et al. Generation and analysis of the improved human HAL9/10 antibody phage display libraries. BMC BIOTECHNOLOGY 15:-(2015).
- El-Sayed, KMF; Paris, S; et al. Periodontal regeneration employing gingival margin-derived stem/progenitor cells: an animal study. JOURNAL OF CLINICAL PERIODONTOLOGY 39:861-870(2012).
