GUCA2B
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Official Full Name
guanylate cyclase activator 2B (uroguanylin) -
Overview
Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. -
Synonyms
GUCA2B;guanylate cyclase activator 2B (uroguanylin);UGN;GCAP-II;Guanylate cyclase activator 2B;Guanylate cyclase C-activating peptide 2;Guanylate cyclase C-activating peptide II;Uroguanylin;OTTHUMP00000007927
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293T
- Yeast
- HEK293
- Non
- His
- Myc&DDK
- His&Fc&Avi
- His&SUMO
- GST
Involved Pathway
GUCA2B involved in several pathways and played different roles in them. We selected most pathways GUCA2B participated on our site, such as Myometrial Relaxation and Contraction Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCA2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Myometrial Relaxation and Contraction Pathways | RAMP3,ATF5,CORIN,ADM,GPR182,RGS4,GABPA,CRCP,RGS10,RGS19 |
Protein Function
GUCA2B has several biochemical functions, for example, calcium sensitive guanylate cyclase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCA2B itself. We selected most functions GUCA2B had, and list some proteins which have the same functions with GUCA2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium sensitive guanylate cyclase activator activity | GUCA1B,GUCA1A,GUCA1D,RCVRN,GUCA1C,GUCA1E,GUCA1G |
Interacting Protein
GUCA2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCA2B here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCA2B.
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References
- Tain, YL; Lee, CT; et al. Long-Term Effects of Maternal Citrulline Supplementation on Renal Transcriptome Prevention of Nitric Oxide Depletion-Related Programmed Hypertension: The Impact of Gene-Nutrient Interactions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:23255-23268(2014).
- Camilleri, M; Carlson, P; et al. RNA sequencing shows transcriptomic changes in rectosigmoid mucosa in patients with irritable bowel syndrome-diarrhea: a pilot case-control study. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 306:C1089-C1098(2014).
