GTPBP1
-
Official Full Name
GTP binding protein 1 -
Overview
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. -
Synonyms
GTPBP1;GTP binding protein 1;GTP-binding protein 1;GP 1;HSPC018;G protein 1;GP1;G-protein 1;OTTHUMP00000028811;GP-1
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
GTPBP1 involved in several pathways and played different roles in them. We selected most pathways GTPBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GTPBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GTPBP1 has several biochemical functions, for example, GTP binding,GTPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTPBP1 itself. We selected most functions GTPBP1 had, and list some proteins which have the same functions with GTPBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | SEPT3,TUBA8L3,EIF2B1,ARL16,EEF1A1B,RHOGA,RAB35B,RRAGA,TUBA1L,REM2 |
| translation initiation factor activity | AGO2,EIF2S1,EIF4A2,EIF4E2,EIF6,EIF4H,EIF3E,EIF3B,EIF2S1A,EIF2S2 |
| poly(A) RNA binding | TMEM38A,PWP2,ZCCHC3,OASL1,EIF3E,RPSA,CCDC86,U2SURP,NSBP1,RTF1 |
| GTPase activity | EEF1A1B,HBS1L,MFN1,TUBA1L2,RAB35,RABL5,RAB42A,GFM1,ARF1,RAB2B |
Interacting Protein
GTPBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTPBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTPBP1.
pi3p;Cit;ssrna_ug;HDGF;Eif3e;IRF5;Rpl35;Gspt1;CHAMP1;CDC5L;Rrbp1
Resources
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References
- Ranjan, P; Kashyap, RS; et al. CELLULAR ORGANELLES FACILITATE DIMERIZATION OF A NEWLY IDENTIFIED ARF FROM CHLAMYDOMONAS REINHARDTII. JOURNAL OF PHYCOLOGY 50:1137-1145(2014).
- Tong, JHM; Lung, RWM; et al. Characterization of rare transforming KRAS mutations in sporadic colorectal cancer. CANCER BIOLOGY & THERAPY 15:768-776(2014).
