GTF3A

  • Official Full Name

    general transcription factor IIIA

  • Overview

    The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]

  • Synonyms

    GTF3A;general transcription factor IIIA;AP2;TFIIIA;transcription factor IIIA

Recombinant Proteins

  • Human
  • Rat
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • His&T7
  • His
  • GST
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
GTF3A-1057H Recombinant Human GTF3A protein, His & T7-tagged E.coli Human His&T7 Val71~Gly365
GTF3A-2746R Recombinant Rat GTF3A Protein Mammalian Cells Rat His
GTF3A-3806C Recombinant Chicken GTF3A Mammalian Cells Chicken His
GTF3A-4461H Recombinant Human GTF3A Protein, GST-tagged Wheat Germ Human GST
GTF3A-7366M Recombinant Mouse GTF3A Protein Mammalian Cells Mouse His
Gtf3a-1605M Recombinant Mouse Gtf3a Protein, His&GST-tagged E.coli Mouse His&GST Gly166-Cys364
Gtf3a-1681R Recombinant Rat Gtf3a protein, His & T7-tagged E.coli Rat His&T7 Val69~His363
GTF3A-2400R Recombinant Rat GTF3A Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
GTF3A-2400R-B Recombinant Rat GTF3A Protein Pre-coupled Magnetic Beads HEK293 Rat
GTF3A-3996M Recombinant Mouse GTF3A Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
GTF3A-3996M-B Recombinant Mouse GTF3A Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    GTF3A involved in several pathways and played different roles in them. We selected most pathways GTF3A participated on our site, such as Gene Expression,RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription,RNA Polymerase III Transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription PTRFB,GTF3AB,MBD3,GTF3AA,GTF3C5,TFB2M,MTERF,CBX3,POU2F1B,POU2F1
    RNA Polymerase III Transcription Initiation ZNF143B,GTF3AB,SNAPC4,POU2F1B,SNAPC2,POLR3GLA,ZNF143,ZNF143A,SNAPC5,SNAPC1
    RNA Polymerase III Transcription SNAPC4,POLR3GLA,GTF3C2,SNAPC2,BRF1,GTF3AB,GTF3AA,SNAPC1,BRF1B,GTF3C3
    RNA Polymerase III Transcription Initiation From Type 1 Promoter BRF1B,GTF3AB,GTF3AA,GTF3C4,BRF1,GTF3C5,GTF3C2,POLR3GLA,GTF3C3
    Gene Expression DARS,NFIA,POLR3C,NR5A1B,GATAD2AB,MED8,ZNF3,WDR77,TPRKB,PRMT5

    Protein Function

    GTF3A has several biochemical functions, for example, DNA binding,RNA binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF3A itself. We selected most functions GTF3A had, and list some proteins which have the same functions with GTF3A. You can find most of the proteins on our site.

    Function Related Protein
    nucleic acid binding EHD4,ZNF740B,GPANK1,PRKRIRB,ZCCHC18,MTERF2,BCL11AB,HNRNPA1A,SSX3,CPSF1
    metal ion binding CYGB2,GALNTL5,ARAP2,IRF2BP2,MICAL2,MMP1A,MARCH5L,KLF10,BMP1A,TRP53
    transcription factor activity, sequence-specific DNA binding CBFA2T2,HOXD3,FOXO3A,EGR2A,NFKB1,HOMEZB,SNAPC4,EGR1,TBX19,NKX3
    DNA binding HOXD11A,CARF,NR5A2,ZBTB26,HIST1H3D,ZNF653,HIST1H2BM,ZFP821,NEUROD6B,HIST1H3F
    RNA binding AGFG1,PABPC5,DPPA5A,IGHMBP2,NANOS3,RPP14,EIF4G2B,ADARB1A,EXOSC5,SETD1BA

    Interacting Protein

    GTF3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF3A.

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