GSG2
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Official Full Name
germ cell associated 2 (haspin) -
Overview
Required for normal alignment of chromosomes at metaphase. Phosphorylates histone H3 'Thr-3' during mitosis. -
Synonyms
GSG2;germ cell associated 2 (haspin);HASPIN;serine/threonine-protein kinase haspin;H-haspin;germ cell-specific gene 2 protein;haploid germ cell-specific nuclear protein kinase
Recombinant Proteins
- Human
- Mouse
- Sf9 Cells
- Mammalian Cells
- HEK293
- Sf21 Cells
- GST
- Non
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GSG2-1586H | Recombinant Human Germ Cell Associated 2 (haspin), GST-tagged | Sf9 Cells | Human | GST | 470-end a.a. |
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| GSG2-29180TH | Recombinant Human GSG2 | Sf9 Cells | Human | Non | 329 amino acids |
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| GSG2-7316M | Recombinant Mouse GSG2 Protein | Mammalian Cells | Mouse | His |
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| GSG2-756HCL | Recombinant Human GSG2 cell lysate | Human | Non |
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| GSG2-3961M | Recombinant Mouse GSG2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GSG2-3961M-B | Recombinant Mouse GSG2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GSG2-4493HF | Active Recombinant Full Length Human GSG2 Protein, GST-tagged | Sf21 Cells | Human | GST | Full L. 1-798 |
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Involved Pathway
GSG2 involved in several pathways and played different roles in them. We selected most pathways GSG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GSG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GSG2 has several biochemical functions, for example, ATP binding,histone kinase activity (H3-T3 specific),protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSG2 itself. We selected most functions GSG2 had, and list some proteins which have the same functions with GSG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TIMM21,APBA3,PLUNC,APBB1,SAP18,CHD2,ANKRD32,MRM1,SPA17,ANK1 |
| histone kinase activity (H3-T3 specific) | VRK1 |
| ATP binding | CSNK1G2,IFIH1,ASS1,MYO1EB,SMC2,NTRK3A,CLK2,ACTR2A,MYH7,PRKG1A |
| protein kinase activity | FASTKD3,PANK1A,KALRN,CDKL3,BSK146,PLK5,GRK7B,SGK196,MAP2K2B,MAP2K4B |
Interacting Protein
GSG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSG2.
HSP90AB1;H3F3A;KPNA6;MYC;MATR3;FBXL6;THAP11;EHMT1;HERC5
Resources
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References
- Sato, S; Maeda, C; et al. DNA Methylation-dependent Modulator of Gsg2/Haspin Gene Expression. JOURNAL OF REPRODUCTION AND DEVELOPMENT 57:526-533(2011).
- Gohbara, A; Katagiri, K; et al. In Vitro Murine Spermatogenesis in an Organ Culture System. BIOLOGY OF REPRODUCTION 83:261-267(2010).
