GSC2
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Official Full Name
goosecoid homeobox 2 -
Overview
Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development. -
Synonyms
GSC2;goosecoid homeobox 2;goosecoid like , GSCL;homeobox protein goosecoid-2;GSC-2;GSC-L;GSCL
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GSC2-2356H | Recombinant Human GSC2 Protein, His-tagged | E.coli | Human | His |
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| GSC2-5389H | Recombinant Human GSC2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GSC2-5620HF | Recombinant Full Length Human GSC2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 205 amino acids |
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Involved Pathway
GSC2 involved in several pathways and played different roles in them. We selected most pathways GSC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GSC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GSC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GSC2 itself. We selected most functions GSC2 had, and list some proteins which have the same functions with GSC2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
GSC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSC2.
Resources
Research Area
Early Endodermal Lineage MarkersEarly Mesodermal Lineage Markers
Pluripotent Stem Cell Transcription Factors
Ectodermal Lineage Markers
Endodermal Lineage Markers
Mesodermal Lineage Markers
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References
- Zhang, HH; Liu, XW; et al. Astrometric calibration of the Xuyi Schmidt Telescope Photometric Survey of the Galactic Anti-center (XSTPS-GAC). RESEARCH IN ASTRONOMY AND ASTROPHYSICS 14:456-470(2014).
- Nemeth, P; Kawka, A; et al. A selection of hot subluminous stars in the GALEX survey - II. Subdwarf atmospheric parameters. MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY 427:2180-2211(2012).
