GRID1
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Official Full Name
glutamate receptor, ionotropic, delta 1 -
Overview
This gene encodes a subunit of glutamate receptor channels. These channels mediate most of the fast excitatory synaptic transmission in the central nervous system and play key roles in synaptic plasticity. -
Synonyms
GRID1;glutamate receptor, ionotropic, delta 1;glutamate receptor delta-1 subunit;KIAA1220;GluR delta 1;GluR delta 1 subunit;GluR delta-1 subunit;Glutamate receptor delta 1 subunit;Glutamate receptor ionotropic delta 1;GRID 1;GRID1_HUMAN;OTTHUMP00000020002;OTTHUMP00000020003
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
GRID1 involved in several pathways and played different roles in them. We selected most pathways GRID1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRID1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | TRHR,TAAR12J,GRM2A,MTNR1BB,BDKRB1,CSH,LPAR3,GABRR2,F2RL1,NPY6R |
Protein Function
GRID1 has several biochemical functions, for example, extracellular-glutamate-gated ion channel activity,ionotropic glutamate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRID1 itself. We selected most functions GRID1 had, and list some proteins which have the same functions with GRID1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ionotropic glutamate receptor activity | GRIA2A,GRIA4,GRIN2A,GRIA4B,GRID2,GRIA2,GRIA1A,GRIN1B,GRIK5,GRIA4A |
| extracellular-glutamate-gated ion channel activity | GRIA2B,GRIA1,GRIN1B,GRIK1,GRIK2,GRIN2B,GRIK3,GRIA1A,GRIN2A,GRIK5 |
Interacting Protein
GRID1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRID1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRID1.
Resources
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References
- Livide, G; Patriarchi, T; et al. GluD1 is a common altered player in neuronal differentiation from both MECP2-mutated and CDKL5-mutated iPS cells. EUROPEAN JOURNAL OF HUMAN GENETICS 23:195-201(2015).
- Ai, HS; Yang, B; et al. Population history and genomic signatures for high-altitude adaptation in Tibetan pigs. BMC GENOMICS 15:-(2014).
