GPR75

  • Official Full Name

    G protein-coupled receptor 75

  • Overview

    GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.

  • Synonyms

    GPR75;G protein-coupled receptor 75;probable G-protein coupled receptor 75;WI 31133;GPRchr2;WI31133;MGC132002

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Mus musculus
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cell
  • Yeast
  • Wheat Germ
  • In Vitro Cell Free System
  • E.coli expression system
  • His
  • Non
  • Fc
  • mFc
  • His&EGFP
  • His&SUMO
  • His&Fc&Avi
  • His&Flag&HA
Cat.# Product name Source (Host) Species Tag Protein Length Price
GPR75-13487H Recombinant Human GPR75, His-tagged E.coli Human His 376-540a.a.
GPR75-3957H Active Recombinant Human GPR75 Full Length Transmembrane protein(Nanodisc) HEK293 Human Non Full L.
GPR75-40H Recombinant Human GPR75 Protein(Met1-Thr46), hFc-tagged HEK293 Human Fc Met1-Thr46
GPR75-41H Recombinant Human GPR75 Protein(Met1-Thr46), mFc-tagged HEK293 Human mFc Met1-Thr46
GPR75-1957R Recombinant Rhesus monkey GPR75 Protein, His-tagged Mammalian Cell Rhesus macaque His
GPR75-5779HCL Recombinant Human GPR75 293 Cell Lysate HEK293 Human Non
GPR75-0493H Recombinant Human GPR75 Protein (M1-V540 end), eGFP, 10×His tagged Mammalian cell Human His&EGFP M1-V540 end
GPR75-121H Recombinant Human GPR75 protein(GPR75), His-SUMO-tagged E.coli Human His&SUMO Cytoplasmic Domain
GPR75-122H Recombinant Human GPR75 protein(GPR75), His-tagged Yeast Human His Cytoplasmic Domain
GPR75-1778R Recombinant Rhesus Macaque GPR75 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GPR75-1778R-B Recombinant Rhesus Macaque GPR75 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GPR75-17H Recombinant Human GPR75-3C-eGFP Protein (M1-V540 end), N-HA/Flag and C-10×His-tagged Mammalian cell Human His&Flag&HA M1-V540 end
GPR75-5262H Recombinant Human GPR75 Protein Wheat Germ Human Non
GPR75-5630HF Recombinant Full Length Human GPR75 Protein In Vitro Cell Free System Human Full L. 126 amino acids
RFL13027HF Recombinant Full Length Human Probable G-Protein Coupled Receptor 75(Gpr75) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-540)
RFL2084MF Recombinant Full Length Mouse Probable G-Protein Coupled Receptor 75(Gpr75) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-540)

    Involved Pathway

    GPR75 involved in several pathways and played different roles in them. We selected most pathways GPR75 participated on our site, such as GPCRs, Class A Rhodopsin-like, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR75 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    GPCRs, Class A Rhodopsin-like CCRL2,NMUR1,OPN1LW,GPR31,SSTR2,GPR85,GPR18,GPR45,GPR50,CCR1

    Protein Function

    GPR75 has several biochemical functions, for example, C-C chemokine receptor activity,G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR75 itself. We selected most functions GPR75 had, and list some proteins which have the same functions with GPR75. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity GRM8,TAAR11,RXFP3,CHRM5B,GPR55,MC5RB,OLFR486,AGTR1A,BAI2,NPFFR1L3
    C-C chemokine receptor activity CCR1L1,CCR6A,CCR7,CCR1,CCR9,CCBP2,CCR3,CCR6,CCR10,CCR8

    Interacting Protein

    GPR75 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR75 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR75.

    Resources

    Research Area

    Chemokine Receptors

    References

    • Robledo, G; Gonzalez-Gay, MA; et al. NPSR1 Gene Is Associated with Reduced Risk of Rheumatoid Arthritis. JOURNAL OF RHEUMATOLOGY 39:1166-1170(2012).
    • Coral, S; Covre, A; et al. Epigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications. BRITISH JOURNAL OF CANCER 107:1116-1124(2012).

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