GPN1
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Official Full Name
GPN-loop GTPase 1 -
Overview
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. -
Synonyms
GPN1;GPN-loop GTPase 1;XAB1, XPA binding protein 1 , XPA binding protein 1, GTPase;ATPBD1A;MBDIN;NTPBP;RNA polymerase II associated protein 4;RPAP4;XPA-binding protein 1;ATP(GTP)-binding protein;MBD2-interacting protein;XPA binding protein 1,
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPN1-13429H | Recombinant Human GPN1, GST-tagged | E.coli | Human | GST | 66-374a.a. | |
| GPN1-6847H | Recombinant Human GPN-Loop GTPase 1, His-tagged | E.coli | Human | His | 1-374aa |
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| GPN1-1934HCL | Recombinant Human GPN1 cell lysate | Human | Non |
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| GPN1-2242H | Recombinant Human GPN1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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Involved Pathway
GPN1 involved in several pathways and played different roles in them. We selected most pathways GPN1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GPN1 has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPN1 itself. We selected most functions GPN1 had, and list some proteins which have the same functions with GPN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | RAB24,RAB14,ARF3,RAB5B,RAB11B,RAB9A,TUBA3C,TUBB2B,RAB1BB,RAB25A |
| protein binding | ALDH3B1,TNFAIP1,GPSM2,SUPT4H1,ATN1,APOL1,TRAPPC2L,KCNJ5,Ctsl,ASCL4 |
| GTP binding | IRGQ2,RAP1A,GNA15.1,SRP54,RALBB,GBP5,EEF2B,RAB31,MXG,EHD2 |
Interacting Protein
GPN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPN1.
GPN3;gtp;CSNK2A1;WDR48;ZBED1;XPA;fliG;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;Trip11;XRCC3;Pfdn2;POLR1A;Ruvbl1;POLR2F;POLR2G;POLR3E
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References
- Reyes-Pardo, H; Barbosa-Camacho, AA; et al. A nuclear export sequence in GPN-loop GTPase 1, an essential protein for nuclear targeting of RNA polymerase II, is necessary and sufficient for nuclear export. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1823:1756-1766(2012).
