GPD2
-
Official Full Name
glycerol-3-phosphate dehydrogenase 2 (mitochondrial) -
Overview
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene. -
Synonyms
GPD2;glycerol-3-phosphate dehydrogenase 2 (mitochondrial);glycerol-3-phosphate dehydrogenase, mitochondrial;mitochondrial;GDH2;Glycerol 3 phosphate dehydrogenase 2 (mitochondrial);Glycerol 3 phosphate dehydrogenase 2;Glycerol 3 phosphate dehydrogenase mitochondrial;Glycerol-3-phosphate dehydrogenase;GPD 2;GPD M;GPD-M;GPDH M;GPDH-M;GPDM;GPDM_HUMAN;mGPDH;Mitochondrial glycerophosphate dehydrogenase;mtGPD;OTTHUMP00000162788;OTTHUMP00000204452;OTTHUMP00000204453;OTTHUMP00000204458
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- Yeast(strain SC5314 / ATCC MYA-2876)
- E.coli
- Human
- Mammalian Cell
- HEK293
- Yeast
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- N-His&C-Myc
- GST
Involved Pathway
GPD2 involved in several pathways and played different roles in them. We selected most pathways GPD2 participated on our site, such as Glycerophospholipid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | CHPT1,LCAT,PHYKPL,PNPLA6,PEMT,CDIPT,GPD1C,PCYT1AA,PLD1,TESCA |
Protein Function
GPD2 has several biochemical functions, for example, calcium ion binding,glycerol-3-phosphate dehydrogenase activity,sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPD2 itself. We selected most functions GPD2 had, and list some proteins which have the same functions with GPD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycerol-3-phosphate dehydrogenase activity | GPD1 |
| calcium ion binding | RHOT2,IHH,FBLN7,PADI6,CSN2,PCDH2G3,S100V2,DLA,PLA2G4B,NELL2A |
Interacting Protein
GPD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPD2.
E2F3
Resources
Related Services
Related Products
References
- Johansson, A; Lau, J; et al. Endothelial cell signalling supports pancreatic beta cell function in the rat. DIABETOLOGIA 52:2385-2394(2009).
