GPBP1
-
Official Full Name
GC-rich promoter binding protein 1 -
Overview
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
GPBP1;GC-rich promoter binding protein 1;vasculin;DKFZp761C169;GC rich promoter binding protein 1;GPBP;MGC126339;Vascular wall linked;vascular wall-linked protein;SSH6
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&SUMO
- Myc&DDK
- His&Fc&Avi
- GST
Involved Pathway
GPBP1 involved in several pathways and played different roles in them. We selected most pathways GPBP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GPBP1 has several biochemical functions, for example, DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPBP1 itself. We selected most functions GPBP1 had, and list some proteins which have the same functions with GPBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZFP287,ZNF32,TA,CENPW,SNAPC3,TFCP2,SMYD1,HIST3H3,SSBP3A,SCML2 |
| protein binding | HIST1H4G,NAP1L4,LEF1,FANCF,SYCE1,RUVBL1,ADAMTSL3,CTSK,NMNAT1,TNFAIP3 |
| transcription factor activity, sequence-specific DNA binding | HNF1BB,PGBD1,ZKSCAN17,ZNF12,SOX9,ZFP161,RUNX2A,KDM3A,NME2,NEUROD1 |
Interacting Protein
GPBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPBP1.
C20orf195;PLEKHF2;MCRS1;DNAL4
Resources
Related Services
Related Products
References
