GPBAR1
-
Official Full Name
G protein-coupled bile acid receptor 1 -
Synonyms
GPBAR1;G protein-coupled bile acid receptor 1;19680;ENSG00000179921;BG37;TGR5;M-BAR;GPCR19;GPR131;2q35;MGC40597;G-protein coupled bile acid receptor 1;G-protein coupled bile acid receptor 1;hBG37;hGPCR19;membrane bile acid receptor;G-protein coupled receptor GPCR19;membrane-type receptor for bile acids;G-protein coupled bile acid receptor BG37
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Bovine
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&Flag
- His&Fc&Avi
- His&KSI
Involved Pathway
GPBAR1 involved in several pathways and played different roles in them. We selected most pathways GPBAR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (s) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPBAR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (s) signalling events | PTHLH,ADCYAP1R1,DRD5,RLN2,PTH2,CRHR2,POMCB,PTHLHA,ADCYAP1B,ADORA2A |
| GPCR ligand binding | FFAR3,CCR3,PPY,ZFPM2B,GPR4,NTS,TAC1,SST1.1,NPS,CALCA |
| Signaling by GPCR | ANXA1C,RGS21,ARHGEF1B,VIP2,PNOC,RGR,EMR1,CXCR7B,OXGR1A.1,OXGR1A.2 |
| GPCR downstream signaling | PYY,GPR65,RGS10,HRH3,ANXA1B,RHOB,TRIO,OR56A1,OPN1MW,NPS |
| Class A/1 (Rhodopsin-like receptors) | RHOL,SSTR5,EDNRA,ADORA3,CYSLTR1,OPN1MW2,PYY,PYYA,CCL35.1,PENKB |
| Signal Transduction | GPR4,SHRPRBCK1R,SOX6,RNF43,ADM2,PTHLH,RGS18,SPRY1,CRABP1,AXL |
Protein Function
GPBAR1 has several biochemical functions, for example, G-protein coupled bile acid receptor activity,bile acid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPBAR1 itself. We selected most functions GPBAR1 had, and list some proteins which have the same functions with GPBAR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| bile acid receptor activity | NR1H4 |
Interacting Protein
GPBAR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPBAR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPBAR1.
dtpA;q5nep4_fratt;frwC;q7cj45_yerpe;fklB;q81ws3_bacan;q8czw8_yerpe;lexA
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