GOLPH3
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Official Full Name
golgi phosphoprotein 3 (coat-protein) -
Overview
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008] -
Synonyms
GOLPH3;golgi phosphoprotein 3 (coat-protein);GOPP1;GPP34;MIDAS;Golgi phosphoprotein 3;coat-protein;golgi protein;coat protein GPP34;golgi-associated protein;mitochondrial DNA absence factor;golgi peripheral membrane protein 1, 34 kDa
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- E.coli
- In Vitro Cell Free System
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GOLPH3-1611Z | Recombinant Zebrafish GOLPH3 | Mammalian Cell | Zebrafish | His |
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| GOLPH3-26785TH | Recombinant Human GOLPH3 | Wheat Germ | Human | Non | 298 amino acids |
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| GOLPH3-7068M | Recombinant Mouse GOLPH3 Protein | Mammalian Cell | Mouse | His |
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| GOLPH3-728HCL | Recombinant Human GOLPH3 cell lysate | Human | Non |
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| GOLPH3-1157H | Recombinant Human GOLPH3 protein, His-tagged | E.coli | Human | His | 1-298aa |
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| GOLPH3-201HF | Recombinant Full Length Human GOLPH3 Protein | In Vitro Cell Free System | Human | Full L. 298 amino acids |
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| GOLPH3-2051H | Recombinant Human GOLPH3 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Golph3-3270M | Recombinant Mouse Golph3 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| GOLPH3-3796M | Recombinant Mouse GOLPH3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GOLPH3-3796M-B | Recombinant Mouse GOLPH3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GOLPH3-5113H | Recombinant Human GOLPH3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GOLPH3-5449HF | Recombinant Full Length Human GOLPH3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 298 amino acids |
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Involved Pathway
GOLPH3 involved in several pathways and played different roles in them. We selected most pathways GOLPH3 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with GOLPH3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | SIX4,SPI1,SIX1,Aff1,CCNA1,IGFBP3,PAX7,NFKB1,HDAC1,ZBTB17 |
Protein Function
GOLPH3 has several biochemical functions, for example, enzyme binding,phosphatidylinositol-4-phosphate binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GOLPH3 itself. We selected most functions GOLPH3 had, and list some proteins which have the same functions with GOLPH3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GALT,FRMD6,NEBL,SS18,PCDH17,ACVRL1,Apba1,ATP6V1G1,GAP43,C10orf35 |
| enzyme binding | NOTCH3,KAT8,TTN,PYCARD,GSTM7,BIRC5,CUTA,ARRB2,WWOX,BCR |
| phosphatidylinositol-4-phosphate binding | RS1,ARFIP1,GOLPH3L,CLSTN2,SESTD1,SNX24,FAM21C,ARFIP2,OSBPL8,COL4A3BP |
Interacting Protein
GOLPH3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GOLPH3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GOLPH3.
MYO18A;pi4p;GCNT1;vpr;ARL6IP1
Resources
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References
- Buschman, MD; Rahajeng, J; et al. GOLPH3 Links the Golgi, DNA Damage, and Cancer. CANCER RESEARCH 75:624-627(2015).
- Sechi, S; Frappaolo, A; et al. The roles of the oncoprotein GOLPH3 in contractile ring assembly and membrane trafficking during cytokinesis. BIOCHEMICAL SOCIETY TRANSACTIONS 43:117-121(2015).
