GNRH2
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Official Full Name
gonadotropin-releasing hormone 2 -
Overview
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide hormone have been found for this gene. -
Synonyms
GNRH2;gonadotropin-releasing hormone 2;progonadoliberin-2;GnRH II;GnRH-associated peptide II;Gonadoliberin II;Gonadotropin-releasing hormone II;Luliberin II;Luteinizing hormone-releasing hormone II;Progonadoliberin 2;Progonadoliberin II;GnRH-II;LH-RHII
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- HEK293
- Mammalian Cells
- Wheat Germ
- E.coli
- In Vitro Cell Free System
- His
- Fc
- Non
- His&Fc&Avi
- GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNRH2-178H | Recombinant Human GNRH2, His-tagged | HEK293 | Human | His | 24-120 a.a. |
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| GNRH2-1916R | Recombinant Rhesus monkey GNRH2 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| GNRH2-681H | Recombinant Human GNRH2 protein(Gln24-Val120), hFc-tagged | HEK293 | Human | Fc | Gln24-Val120 |
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| GNRH2-9620Z | Recombinant Zebrafish GNRH2 | Mammalian Cells | Zebrafish | His |
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| GNRH2-5838HCL | Recombinant Human GNRH2 293 Cell Lysate | HEK293 | Human | Non |
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| GNRH2-1736R | Recombinant Rhesus Macaque GNRH2 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| GNRH2-1736R-B | Recombinant Rhesus Macaque GNRH2 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| GNRH2-2979H | Recombinant Human GNRH2 Protein (Gln24-Val120), C-His tagged | Mammalian Cells | Human | His | Gln24-Val120 |
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| GNRH2-5098H | Recombinant Human GNRH2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GNRH2-529H | Recombinant Human GNRH2 Protein (24-120 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 24-120 aa |
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| GNRH2-5410HF | Recombinant Full Length Human GNRH2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 120 amino acids |
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Involved Pathway
GNRH2 involved in several pathways and played different roles in them. We selected most pathways GNRH2 participated on our site, such as GnRH signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNRH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| GnRH signaling pathway | MAP2K4,GRB2A,ITPR1,GRB2,PTK2BB,MAPK7,ATF4B1,KRAS,CDC42L,MAPK3 |
Protein Function
GNRH2 has several biochemical functions, for example, gonadotropin hormone-releasing hormone activity,gonadotropin-releasing hormone receptor binding,hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNRH2 itself. We selected most functions GNRH2 had, and list some proteins which have the same functions with GNRH2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gonadotropin-releasing hormone receptor binding | GNRH1,GNRH3 |
| hormone activity | GALP,PRL6A1,INS-IGF2,IGF3,STC1L,Retnla,AGT,BNP,UTS2D,PTHLH |
| gonadotropin hormone-releasing hormone activity | GNRH3,GNRH1 |
Interacting Protein
GNRH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNRH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNRH2.
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References
- Sand, E; Bergvall, M; et al. Expression and distribution of GnRH, LH, and FSH and their receptors in gastrointestinal tract of man and rat. REGULATORY PEPTIDES 187:24-28(2013).
