GINS2
-
Official Full Name
GINS complex subunit 2 (Psf2 homolog) -
Overview
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and;Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast;and Xenopus egg extracts (Ueno et al., 2005 (PubMed 16287864)). See GINS1 for additional information about the GINS;complex. -
Synonyms
GINS2;GINS complex subunit 2 (Psf2 homolog);DNA replication complex GINS protein PSF2;Pfs2;PSF2;anti PSF2;GINS complex subunit 2;HSPC037;OTTHUMP00000175001
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- T7
- Non
- Myc&DDK
- His&Fc&Avi
- GST
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GINS2-13262H | Recombinant Human GINS2, His-tagged | E.coli | Human | His | 1-185a.a. | |
| GINS2-153H | Recombinant Human GINS2 protein, T7-tagged | E.coli | Human | T7 | 185 a.a. |
|
| GINS2-3037Z | Recombinant Zebrafish GINS2 | Mammalian Cell | Zebrafish | His |
|
|
| GINS2-3054H | Recombinant Human GINS Complex Subunit 2 (Psf2 Homolog), T7-tagged | E.coli | Human | T7 | 1-185 a.a. |
|
| GINS2-54H | Recombinant Human GINS2 protein, His-tagged | E.coli | Human | His | 200aa(including fusion tag) |
|
| GINS2-6359M | Recombinant Mouse GINS2 Protein | Mammalian Cell | Mouse | His |
|
|
| GINS2-5933HCL | Recombinant Human GINS2 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Gins2-3210M | Recombinant Mouse Gins2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
|
| GINS2-3561M | Recombinant Mouse GINS2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| GINS2-3561M-B | Recombinant Mouse GINS2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| GINS2-4909H | Recombinant Human GINS2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| GINS2-4962H | Recombinant Human GINS2 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 1-185aa |
|
| GINS2-5264HF | Recombinant Full Length Human GINS2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 185 amino acids |
|
Involved Pathway
GINS2 involved in several pathways and played different roles in them. We selected most pathways GINS2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,DNA Replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with GINS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Synthesis of DNA | GINS3,GINS1,GINS4 |
| S Phase | ESCO1,GINS1,MYCA,ESCO2,GINS3,GINS4 |
| DNA Replication | MCM6L,MCM3L,POLD1,RNASEH2C,POLD4,RPA3,LIG1,FEN1,PRIM2,POLE |
| DNA strand elongation | GINS4,GINS1,GINS3,DNA2 |
| Cell Cycle, Mitotic | GORASP2,PDS5A,NINL,H3F3D,GMNN,NUMA1,TOP2A,CENPP,NUP35,CEP63 |
| Cell cycle | CEP70,ESCO1,ANAPC1,GADD45B,H3F3B.1,TGFB1,AKAP9,ANAPC7,TSGA14,DSN1 |
| Unwinding of DNA | GINS3,GINS1,GINS4 |
Protein Function
GINS2 has several biochemical functions, for example, contributes_to 3-5 DNA helicase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GINS2 itself. We selected most functions GINS2 had, and list some proteins which have the same functions with GINS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HIC1,SIN3B,TNNC2,NLGN3,VPS26A,CCNB3,HMGB4,FAM131C,LRRK1,KLK6 |
| contributes_to 3-5 DNA helicase activity | GINS4 |
Interacting Protein
GINS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GINS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GINS2.
GINS4;MCMBP;CHEK2
Resources
Related Services
Related Products
References
