GINS1
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Official Full Name
GINS complex subunit 1 (Psf1 homolog) -
Overview
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and;Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in;yeast and Xenopus egg extracts (Ueno et al., 2005 (PubMed 16287864)). -
Synonyms
GINS1;GINS complex subunit 1 (Psf1 homolog);DNA replication complex GINS protein PSF1;KIAA0186;PSF1;GINS complex subunit 1;partner of sld five-1;partner of sld5;PSF1 homolog;RP4-691N24.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GINS1-1589Z | Recombinant Zebrafish GINS1 | Mammalian Cell | Zebrafish | His |
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| GINS1-1973C | Recombinant Chicken GINS1 | Mammalian Cell | Chicken | His |
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| GINS1-5934HCL | Recombinant Human GINS1 293 Cell Lysate | HEK293 | Human | Non |
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| GINS1-4908H | Recombinant Human GINS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| GINS1-5263HF | Recombinant Full Length Human GINS1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 196 amino acids |
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Involved Pathway
GINS1 involved in several pathways and played different roles in them. We selected most pathways GINS1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,DNA Replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with GINS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle, Mitotic | CDKN2A,ERCC6L,MAPRE1B,DSN1,CSNK2B,DCTN1A,ARPP19,ESCO2,INCENP,TUBB4B |
| Unwinding of DNA | GINS3,GINS2,GINS4 |
| DNA Replication | POLE,RNASEH1,GINS3,MCM6,RPA2,CDT1,RPA3,RPA4,MCM6L,RNASEH2B |
| Cell cycle | CHEK2,BRCC3,TEX15,CDK6,STIL,CEP164,GORASP2,UBE2V2,PSMC3IP,MAPRE1 |
| DNA strand elongation | GINS3,GINS4,GINS2,DNA2 |
| Synthesis of DNA | GINS2,GINS4,GINS3 |
| S Phase | ESCO2,ESCO1,GINS4,GINS2,GINS3,MYCA |
Protein Function
GINS1 has several biochemical functions, for example, 3-5 DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GINS1 itself. We selected most functions GINS1 had, and list some proteins which have the same functions with GINS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-5 DNA helicase activity | WRN,FBXO18,ERCC3,CDC45 |
Interacting Protein
GINS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GINS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GINS1.
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