GEMIN2
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Official Full Name
GEMIN2 gem (nuclear organelle) associated protein 2 -
Overview
Involved in biogenesis of spliceosomal snRNPs, forms complex with Survival of Motor Neurons (SMN) protein, interacts tightly with spliceosomal proteins and spliceosomal snRNAs U1 and U5. -
Synonyms
GEMIN2;gem (nuclear organelle) associated protein 2;SIP1, survival of motor neuron protein interacting protein 1;gem-associated protein 2;gemin-2;component of gems 2;SMN interacting protein 1-delta;survival of motor neuron protein interacting protein 1;SIP1;SIP1-delta
Recombinant Proteins
- Zebrafish
- Rat
- Chicken
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GEMIN2-2380Z | Recombinant Zebrafish GEMIN2 | Mammalian Cell | Zebrafish | His |
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| GEMIN2-2507R | Recombinant Rat GEMIN2 Protein | Mammalian Cell | Rat | His |
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| GEMIN2-3362C | Recombinant Chicken GEMIN2 | Mammalian Cell | Chicken | His |
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| GEMIN2-627H | Recombinant Human GEMIN2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| GEMIN2-2163R | Recombinant Rat GEMIN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GEMIN2-2163R-B | Recombinant Rat GEMIN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Gemin2-5881M | Recombinant Mouse Gemin2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
GEMIN2 involved in several pathways and played different roles in them. We selected most pathways GEMIN2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with GEMIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA transport | EIF3HA,XPO1,EIF4EA,EIF4G1A,XPO5,ALYREF,XPOT,MAGOH,EIF1B,PABPC1A |
Protein Function
GEMIN2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GEMIN2 itself. We selected most functions GEMIN2 had, and list some proteins which have the same functions with GEMIN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
GEMIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GEMIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GEMIN2.
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References
- Gurol, G; Demiralp, DO; et al. Comparative Proteomic Approach in Rat Model of Absence Epilepsy. JOURNAL OF MOLECULAR NEUROSCIENCE 55:632-643(2015).
- Rafalowska, J; Sulejczak, D; et al. Diverse Expression of Selected SMN Complex Proteins in Humans with Sporadic Amyotrophic Lateral Sclerosis and in a Transgenic Rat Model of Familial Form of the Disease. PLOS ONE 9:-(2014).
